Metamizole EP Impurity E

Name: Metamizole EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-031807

About Metamizole EP Impurity E

Listed under CAS 117-38-4, Metamizole EP Impurity E is a pharmacopeial impurity of Metamizole available from Vaqora Chemicals. Its molecular formula is C12H15N3O4S and its molecular weight is 297.33 g/mol. The IUPAC name is [(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]methanesulfonic acid. Alternative names: Metamizole Sodium - Impurity E and Sulfamidopyrine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Metamizole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Metamizole EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Metamizole

View every impurity, metabolite and intermediate we list for Metamizole.

Metamizole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Metamizole EP Impurity E
Catalogue No.	VQ-031807
CAS Number	117-38-4
IUPAC name	[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]methanesulfonic acid
Molecular formula	C₁₂H₁₅N₃O₄S
Molecular weight	297.33 g/mol
Exact mass	297.0783
Grade	Reference Standard
HSN code	38229090
InChIKey	VRESBCAKEFFDQB-UHFFFAOYSA-N
SMILES	CC1=C(C(=O)N(N1C)C2=CC=CC=C2)NCS(=O)(=O)O
PubChem CID	19145

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	2 / 6
TPSA	98.3 Å²
Synonyms	Metamizole Sodium - Impurity E, Sulfamidopyrine, (Antipyrinylamino)methanesulfonic acid, ((1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino)methanesulfonic acid, Methanesulfonic acid, (antipyrinylamino)-, [(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]methanesulfonic acid, Methanesulfonic acid, ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amino)-, Methanesulfonic acid, 1-((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amino)-, [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amino]methanesulfonic acid, Melaminsulfone

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Metamizole EP Impurity E?

The CAS Registry Number of Metamizole EP Impurity E is 117-38-4. It is also known as Metamizole Sodium - Impurity E, Sulfamidopyrine, (Antipyrinylamino)methanesulfonic acid.

What is the molecular formula and molecular weight of Metamizole EP Impurity E?

Metamizole EP Impurity E has the molecular formula C12H15N3O4S and a molecular weight of 297.33 g/mol. Its IUPAC name is [(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]methanesulfonic acid.

What is Metamizole EP Impurity E used for?

Metamizole EP Impurity E is supplied as a characterised reference material related to Metamizole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Metamizole EP Impurity E can I order?

We supply Metamizole EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Metamizole EP Impurity E?

Yes. Every lot of Metamizole EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Metamizole EP Impurity E be shipped internationally?

Yes. Metamizole EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.