Nintedanib N-Acyl Ethoxy Enolindole

Name: Nintedanib N-Acyl Ethoxy Enolindole
Brand: Vaqora Chemicals
SKU: VQ-045342

About Nintedanib N-Acyl Ethoxy Enolindole

Listed under CAS 1175365-43-1, Nintedanib N-Acyl Ethoxy Enolindole is an impurity of Nintedanib available from Vaqora Chemicals. With the molecular formula C21H19NO5, it has a molar mass of 365.4 g/mol. Systematically, it is named methyl 1-acetyl-3-[ethoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Nintedanib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nintedanib N-Acyl Ethoxy Enolindole in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib N-Acyl Ethoxy Enolindole
Catalogue No.	VQ-045342
CAS Number	1175365-43-1
IUPAC name	methyl 1-acetyl-3-[ethoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate
Molecular formula	C₂₁H₁₉NO₅
Molecular weight	365.4 g/mol
Exact mass	365.1263
Grade	Reference Standard
HSN code	38229090
InChIKey	NSLGYOTXIPMWNZ-UHFFFAOYSA-N
SMILES	CCOC(=C1C2=C(C=C(C=C2)C(=O)OC)N(C1=O)C(=O)C)C3=CC=CC=C3
PubChem CID	66685972

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 5
TPSA	72.9 Å²
Synonyms	1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone, Methyl 1-acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl 1-Acetyl-3-[ethoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate, Methyl(Z)-1-Acetyl-3-[ethoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate, methyl 1-acetyl-3-[ethoxy(phenyl)methylene]-2-oxo-indoline-6-carboxylate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib N-Acyl Ethoxy Enolindole?

The CAS Registry Number of Nintedanib N-Acyl Ethoxy Enolindole is 1175365-43-1. It is also known as 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone, Methyl 1-acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl 1-Acetyl-3-[ethoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate.

What is the molecular formula and molecular weight of Nintedanib N-Acyl Ethoxy Enolindole?

Nintedanib N-Acyl Ethoxy Enolindole has the molecular formula C21H19NO5 and a molecular weight of 365.4 g/mol. Its IUPAC name is methyl 1-acetyl-3-[ethoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate.

What is Nintedanib N-Acyl Ethoxy Enolindole used for?

Nintedanib N-Acyl Ethoxy Enolindole is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib N-Acyl Ethoxy Enolindole can I order?

We supply Nintedanib N-Acyl Ethoxy Enolindole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib N-Acyl Ethoxy Enolindole?

Yes. Every lot of Nintedanib N-Acyl Ethoxy Enolindole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib N-Acyl Ethoxy Enolindole be shipped internationally?

Yes. We export Nintedanib N-Acyl Ethoxy Enolindole worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.