5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-i… 118307-04-3

Name: 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one
Brand: Vaqora Chemicals
SKU: VQ-034744

About 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one

Vaqora Chemicals supplies 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one, an impurity of Ziprasidone registered under CAS number 118307-04-3. The compound has the formula C10H7Cl2NO2, corresponding to a molecular weight of 244.07 g/mol. The IUPAC name is 6-chloro-5-(2-chloroacetyl)-1,3-dihydroindol-2-one. Alternative names: 5-(2-chloroacetyl)-6-chlorooxindole and 5-chloroacetyl-6-chlorooxindole.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Ziprasidone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ziprasidone

View every impurity, metabolite and intermediate we list for Ziprasidone.

Ziprasidone impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one
Catalogue No.	VQ-034744
CAS Number	118307-04-3
IUPAC name	6-chloro-5-(2-chloroacetyl)-1,3-dihydroindol-2-one
Molecular formula	C₁₀H₇Cl₂NO₂
Molecular weight	244.07 g/mol
Exact mass	242.9854
Grade	Reference Standard
HSN code	38229090
InChIKey	LWWVMDRRHHCTMZ-UHFFFAOYSA-N
SMILES	C1C2=CC(=C(C=C2NC1=O)Cl)C(=O)CCl
PubChem CID	3730946

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 2
TPSA	46.2 Å²
Synonyms	5-(2-chloroacetyl)-6-chlorooxindole, 5-chloroacetyl-6-chlorooxindole, 6-chloro-5-(2-chloroacetyl)indolin-2-one, 6-chloro-5-(chloroacetyl)-1,3-dihydro-2H-indol-2-one, 5-chloroacetyl-6-ch, 6-chloro-5-(2-chloro-acetyl)-1,3-dihydro-indol-2-one, 2H-Indol-2-one, 6-chloro-5-(chloroacetyl)-1,3-dihydro-, 5-Cloroacetyl-6-chlorooxindole, 5-(2-Chloro acetyl)-6-chloro oxindole, 5-(2-Chloro acetyl) -6-chloro oxindole, 6-Chloro-5-(chloroacetyl)-1,3-dihydro-2H-indol-2-one, AldrichCPR

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one?

The CAS Registry Number of 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one is 118307-04-3. It is also known as 5-(2-chloroacetyl)-6-chlorooxindole, 5-chloroacetyl-6-chlorooxindole, 6-chloro-5-(2-chloroacetyl)indolin-2-one.

What is the molecular formula and molecular weight of 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one?

5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one has the molecular formula C10H7Cl2NO2 and a molecular weight of 244.07 g/mol. Its IUPAC name is 6-chloro-5-(2-chloroacetyl)-1,3-dihydroindol-2-one.

What is 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one used for?

5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one is supplied as a characterised reference material related to Ziprasidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one can I order?

We supply 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one?

Yes. Every lot of 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one be shipped internationally?

Yes. 5-Chloroacetyl-6-chloro-1,3-dihydroindol-2H-indone-2-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.