Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC)

About Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC)

Fmoc-D-Tyr(tBu)-OH is a protected amino acid carrying the CAS registry number 118488-18-9 with a typical assay of ≥98%. The compound has the formula C28H29NO5, corresponding to a molecular weight of 459.5 g/mol. Systematically, it is named (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid. Alternative names: Fmoc-O-tert-butyl-D-tyrosine and O-(1,1-Dimethylethyl)-N-[.

The material typically appears as white to colourless powder or crystals. Literature values give a melting point of 143-155 °C. Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

It is commonly used for solid-phase peptide synthesis (SPPS), peptide drug discovery, medicinal chemistry and chromatography. It is used across academic and industrial research and diagnostics and biotechnology.

Standard pack sizes are 1 g, 5 g and 25 g, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Solid-phase peptide synthesis (SPPS)
Peptide drug discovery
Medicinal chemistry
Chromatography

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC)
Catalogue No.	VQ-002262
CAS Number	118488-18-9
IUPAC name	(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
Molecular formula	C₂₈H₂₉NO₅
Molecular weight	459.5 g/mol
Exact mass	459.2046
Purity / assay	≥98%
HSN code	29242990
InChIKey	JAUKCFULLJFBFN-RUZDIDTESA-N
SMILES	CC(C)(C)OC1=CC=C(C=C1)C[C@H](C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
PubChem CID	12968135

Physical properties
Physical form	Crystalline
Appearance	White to colourless powder or crystals
Melting point	143-155 °C
LogP (XLogP3)	5.6
H-bond donors / acceptors	2 / 5
TPSA	84.9 Å²
Synonyms	Fmoc-O-tert-butyl-D-tyrosine, (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid, O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tyrosine, Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-D-tyrosine, D-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, (2R)-3-[4-(tert-butoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid, (2R)-3-(4-tert-butoxyphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid, O-tert-Butyl-N-{[(9H-fluoren-9-yl)methoxy](hydroxy)methylidene}tyrosine, O-(1,1-Dimethylethyl)-N-[, 3-(4-tert-Butoxy-phenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid, Nalpha-Fmoc-O-tert-butyl-D-tyrosine, O-tert-Butyl-Nalpha-Fmoc-D-tyrosine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P272, P273, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC)?

The CAS Registry Number of Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC) is 118488-18-9. It is also known as Fmoc-O-tert-butyl-D-tyrosine, (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid, O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tyrosine.

What is the molecular formula and molecular weight of Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC)?

Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC) has the molecular formula C28H29NO5 and a molecular weight of 459.5 g/mol. Its IUPAC name is (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid.

Which grade and pack sizes of Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC) can I order?

We supply Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC) in (≥98%) grade, in 1 g, 5 g, 25 g packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC)?

Yes. Every lot of Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC) be shipped internationally?

Yes. Fmoc-D-Tyr(tBu)-OH, ≥98% (HPLC) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.