Metformin-d6 Hydrochloride

Name: Metformin-d6 Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-031816

About Metformin-d6 Hydrochloride

Metformin-d6 Hydrochloride (CAS 1185166-01-1) is a stable isotope labelled analogue related to Metformin offered by Vaqora Chemicals. The compound has the formula C4H12ClN5, corresponding to a molecular weight of 171.66 g/mol. Common synonyms include Metformin D6 and 1,1-di(methyl-d3)biguanide hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Metformin-d6 Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Metformin

View every impurity, metabolite and intermediate we list for Metformin.

Metformin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Metformin-d6 Hydrochloride
Catalogue No.	VQ-031816
CAS Number	1185166-01-1
IUPAC name	3-(diaminomethylidene)-1,1-bis(trideuteriomethyl)guanidine;hydrochloride
Molecular formula	C₄H₁₂ClN₅
Molecular weight	171.66 g/mol
Exact mass	171.1158
Grade	Reference Standard
HSN code	38229090
InChIKey	OETHQSJEHLVLGH-TXHXQZCNSA-N
SMILES	[2H]C([2H])([2H])N(C(=N)N=C(N)N)C([2H])([2H])[2H].Cl
PubChem CID	45039707

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 1
TPSA	91.5 Å²
Synonyms	Metformin D6, N'-(Diaminomethylidene)-N,N-bis((~2~H_3_)methyl)guanidine--hydrogen chloride (1/1), N'-(Diaminomethylidene)-N,N-bis[(~2~H_3_)methyl]guanidine--hydrogen chloride (1/1), 1,1-di(methyl-d3)biguanide hydrochloride, Metformine D6 hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Metformin-d6 Hydrochloride?

The CAS Registry Number of Metformin-d6 Hydrochloride is 1185166-01-1. It is also known as Metformin D6, N'-(Diaminomethylidene)-N,N-bis((~2~H_3_)methyl)guanidine--hydrogen chloride (1/1), N'-(Diaminomethylidene)-N,N-bis[(~2~H_3_)methyl]guanidine--hydrogen chloride (1/1).

What is the molecular formula and molecular weight of Metformin-d6 Hydrochloride?

Metformin-d6 Hydrochloride has the molecular formula C4H12ClN5 and a molecular weight of 171.66 g/mol.

What is Metformin-d6 Hydrochloride used for?

Metformin-d6 Hydrochloride is supplied as a characterised reference material related to Metformin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Metformin-d6 Hydrochloride can I order?

We supply Metformin-d6 Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Metformin-d6 Hydrochloride?

Yes. Every lot of Metformin-d6 Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Metformin-d6 Hydrochloride be shipped internationally?

Yes. Metformin-d6 Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.