Pyridoxine-d3 Hydrochloride

About Pyridoxine-d3 Hydrochloride

Pyridoxine-d3 Hydrochloride is a stable isotope labelled analogue related to Pyridoxine carrying the CAS registry number 1189921-12-7. The compound has the formula C8H12ClNO3, corresponding to a molecular weight of 208.66 g/mol. It is also known as Pyridoxine-d3 HCl or Vitamin B6-d3 hydrochloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Pyridoxine and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Pyridoxine

View every impurity, metabolite and intermediate we list for Pyridoxine.

Pyridoxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Pyridoxine-d3 Hydrochloride
Catalogue No.	VQ-041770
CAS Number	1189921-12-7
IUPAC name	4,5-bis(hydroxymethyl)-2-(trideuteriomethyl)pyridin-3-ol;hydrochloride
Molecular formula	C₈H₁₂ClNO₃
Molecular weight	208.66 g/mol
Exact mass	208.0694
Grade	Reference Standard
HSN code	38229090
InChIKey	ZUFQODAHGAHPFQ-NIIDSAIPSA-N
SMILES	[2H]C([2H])([2H])C1=NC=C(C(=C1O)CO)CO.Cl
PubChem CID	46782823

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 4
TPSA	73.6 Å²
Synonyms	4,5-Bis(hydroxymethyl)-2-(2H3)methylpyridin-3-ol hydrochloride, Pyridoxine-d3 HCl, Vitamin B6-d3 hydrochloride, Pyridoxine-[2H3].HCl, Pyridoxine-[D3] HCl (Vitamin B6-[D3]), TMIH-0467

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements: P264 + P265, P280, P305 + P354 + P338, P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pyridoxine-d3 Hydrochloride?

The CAS Registry Number of Pyridoxine-d3 Hydrochloride is 1189921-12-7. It is also known as 4,5-Bis(hydroxymethyl)-2-(2H3)methylpyridin-3-ol hydrochloride, Pyridoxine-d3 HCl, Vitamin B6-d3 hydrochloride.

What is the molecular formula and molecular weight of Pyridoxine-d3 Hydrochloride?

Pyridoxine-d3 Hydrochloride has the molecular formula C8H12ClNO3 and a molecular weight of 208.66 g/mol.

What is Pyridoxine-d3 Hydrochloride used for?

Pyridoxine-d3 Hydrochloride is supplied as a characterised reference material related to Pyridoxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pyridoxine-d3 Hydrochloride can I order?

We supply Pyridoxine-d3 Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pyridoxine-d3 Hydrochloride?

Yes. Every lot of Pyridoxine-d3 Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pyridoxine-d3 Hydrochloride be shipped internationally?

Yes. Pyridoxine-d3 Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.