(R,S,R,S)-Nebivolol

About (R,S,R,S)-Nebivolol

(R,S,R,S)-Nebivolol is a high-purity reference standard of Nebivolol carrying the CAS registry number 119365-24-1. The compound has the formula C22H25F2NO4, corresponding to a molecular weight of 405.4 g/mol. It is also known as (S,R,S,R)-Nebivolol or SRSR or RSRS Nebivolol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Nebivolol standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	(R,S,R,S)-Nebivolol
Catalogue No.	VQ-032082
CAS Number	119365-24-1
IUPAC name	(1R)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol
Molecular formula	C₂₂H₂₅F₂NO₄
Molecular weight	405.4 g/mol
Exact mass	405.1752
Grade	Reference Standard
HSN code	38229090
InChIKey	KOHIRBRYDXPAMZ-MTIDIVMFSA-N
SMILES	C1CC2=C(C=CC(=C2)F)O[C@H]1[C@H](CNC[C@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O
PubChem CID	29985107

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	3 / 7
TPSA	71 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R,S,R,S)-Nebivolol?

The CAS Registry Number of (R,S,R,S)-Nebivolol is 119365-24-1. It is also known as (S,R,S,R)-Nebivolol, SRSR or RSRS Nebivolol.

What is the molecular formula and molecular weight of (R,S,R,S)-Nebivolol?

(R,S,R,S)-Nebivolol has the molecular formula C22H25F2NO4 and a molecular weight of 405.4 g/mol. Its IUPAC name is (1R)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol.

What is (R,S,R,S)-Nebivolol used for?

(R,S,R,S)-Nebivolol is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R,S,R,S)-Nebivolol can I order?

We supply (R,S,R,S)-Nebivolol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R,S,R,S)-Nebivolol?

Yes. Every lot of (R,S,R,S)-Nebivolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R,S,R,S)-Nebivolol be shipped internationally?

Yes. We export (R,S,R,S)-Nebivolol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.