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Pharmacopeial Impurities (EP / USP / BP)Reference Standard In stock

Anastrozole EP Impurity H

Synonyms: 3,5-Bis(2-cyano-2-methylethyl)toluene · 3,5-Bis(2-cyanoprop-2-yl)toluene · α1,α1,α3,α3,5-Pentamethyl-1,3-benzenediacetonitrile · 2-[3-(Cyanodimethylmethyl)-5-methylphenyl]-2-methylpropionitrile

CAS No.120511-72-0
FormulaC15H18N2
Mol. weight226.32
Catalogue No.VQ-006242
PurityReference Standard
HSN38229090

Anastrozole EP Impurity H (CAS 120511-72-0) – Anastrozole impurity standard. C15H18N2, MW 226.32. Order from Vaqora Chemicals with COA and global delivery.

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25 mg
50 mg
100 mg
250 mg
500 mg
1 g
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16-section GHS SDS
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About Anastrozole EP Impurity H

Listed under CAS 120511-72-0, Anastrozole EP Impurity H is a pharmacopeial impurity of Anastrozole available from Vaqora Chemicals. Formula C15H18N2, molecular weight 226.32 g/mol. The IUPAC name is 2-[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile. Alternative names: 3,5-Bis(2-cyano-2-methylethyl)toluene and 3,5-Bis(2-cyanoprop-2-yl)toluene.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Anastrozole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

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Related to Anastrozole

View every impurity, metabolite and intermediate we list for Anastrozole.

Anastrozole impurities

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Specifications & identifiers

Chemical identifiers
Product nameAnastrozole EP Impurity H
Catalogue No.VQ-006242
CAS Number120511-72-0
IUPAC name2-[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile
Molecular formulaC15H18N2
Molecular weight226.32 g/mol
Exact mass226.147
GradeReference Standard
HSN code38229090
InChIKeySJECEXNMZXMXNE-UHFFFAOYSA-N
SMILESCC1=CC(=CC(=C1)C(C)(C)C#N)C(C)(C)C#N
PubChem CID16005484
Physical properties
Physical formSolid
LogP (XLogP3)3.5
H-bond donors / acceptors0 / 2
TPSA47.6 Ų
Synonyms3,5-Bis(2-cyano-2-methylethyl)toluene, 3,5-Bis(2-cyanoprop-2-yl)toluene, α1,α1,α3,α3,5-Pentamethyl-1,3-benzenediacetonitrile, 2-[3-(Cyanodimethylmethyl)-5-methylphenyl]-2-methylpropionitrile, 2,2′-(5-Methyl-1,3-phenylene)bis(2-methylpropanenitrile), 2,2'-(5-Methyl-1,3-phenylene)bis(2-methylpropanenitrile), Anastrozole Related Compound A, 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropionitrile), 1,3-Benzenediacetonitrile, alpha1,alpha1,alpha3,alpha3,5-pentamethyl-, Anastrozole impurity H, 2,2'-(5-methyl-1,3-phenylene)-di-(2-methylpropionitrile), 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropiononitrile)

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant
GHS08 Health hazard
Health hazard

Signal word: Danger

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H360May damage fertility or the unborn child
  • H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Anastrozole EP Impurity H?

The CAS Registry Number of Anastrozole EP Impurity H is 120511-72-0. It is also known as 3,5-Bis(2-cyano-2-methylethyl)toluene, 3,5-Bis(2-cyanoprop-2-yl)toluene, α1,α1,α3,α3,5-Pentamethyl-1,3-benzenediacetonitrile.

What is the molecular formula and molecular weight of Anastrozole EP Impurity H?

Anastrozole EP Impurity H has the molecular formula C15H18N2 and a molecular weight of 226.32 g/mol. Its IUPAC name is 2-[3-(2-cyanopropan-2-yl)-5-methylphenyl]-2-methylpropanenitrile.

What is Anastrozole EP Impurity H used for?

Anastrozole EP Impurity H is supplied as a characterised reference material related to Anastrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Anastrozole EP Impurity H can I order?

We supply Anastrozole EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Anastrozole EP Impurity H?

Yes. Every lot of Anastrozole EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Anastrozole EP Impurity H be shipped internationally?

Yes. Anastrozole EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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120511-73-1
Formula
C17H19N5
MW
293.4 g/mol
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