Losartan EP Impurity E

Name: Losartan EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-021261

About Losartan EP Impurity E

Losartan EP Impurity E (CAS 120568-11-8) is a pharmacopeial impurity of Losartan offered by Vaqora Chemicals. The compound has the formula C14H12N4, corresponding to a molecular weight of 236.27 g/mol. Systematically, it is named 5-[2-(4-methylphenyl)phenyl]-2H-tetrazole. It is also known as Losartan Potassium - Impurity E (Freebase) or Candesartan Methyl Impurity.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

This Losartan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Losartan EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Losartan

View every impurity, metabolite and intermediate we list for Losartan.

Losartan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Losartan EP Impurity E
Catalogue No.	VQ-021261
CAS Number	120568-11-8
IUPAC name	5-[2-(4-methylphenyl)phenyl]-2H-tetrazole
Molecular formula	C₁₄H₁₂N₄
Molecular weight	236.27 g/mol
Exact mass	236.1062
Grade	Reference Standard
HSN code	38229090
InChIKey	VWOJMXKARYCRCC-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3
PubChem CID	9794697

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	1 / 3
TPSA	54.5 Å²
Synonyms	Candesartan methyl Impurity, losartan EP Impurity E, Losartan Potassium - Impurity E (Freebase), Candesartan Methyl Impurity, Irbesartan Methyl Impurity, 5-(4'-Methyl-1,1'-biphenyl-2-yl)-1H-tetrazole, 5-[2-(4'-Methylbiphenyl)]tetrazole, 5-(4'-methylbiphenyl-2-yl)-1H-tetrazole, 5-(4'-Methyl-2-biphenyl)tetrazole, Losartan potassium impurity E, 5-(4'-Methyl-1,1'-biphen-2-yl)-1H-tetrazole, 5-[2-(4-Methylbiphenyl)]tetrazole

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Losartan EP Impurity E?

The CAS Registry Number of Losartan EP Impurity E is 120568-11-8. It is also known as Candesartan methyl Impurity, losartan EP Impurity E, Losartan Potassium - Impurity E (Freebase).

What is the molecular formula and molecular weight of Losartan EP Impurity E?

Losartan EP Impurity E has the molecular formula C14H12N4 and a molecular weight of 236.27 g/mol. Its IUPAC name is 5-[2-(4-methylphenyl)phenyl]-2H-tetrazole.

What is Losartan EP Impurity E used for?

Losartan EP Impurity E is supplied as a characterised reference material related to Losartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Losartan EP Impurity E can I order?

We supply Losartan EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Losartan EP Impurity E?

Yes. Every lot of Losartan EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Losartan EP Impurity E be shipped internationally?

Yes. Losartan EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.