N4-Hydroxymethyl Hydrochlorothiazide

Name: N4-Hydroxymethyl Hydrochlorothiazide
Brand: Vaqora Chemicals
SKU: VQ-035284

About N4-Hydroxymethyl Hydrochlorothiazide

Vaqora Chemicals supplies N4-Hydroxymethyl Hydrochlorothiazide, a metabolite or degradation product of Hydrochlorothiazide registered under CAS number 1216599-78-8. With the molecular formula C8H10ClN3O5S2, it has a molar mass of 327.8 g/mol. The IUPAC name is 6-chloro-4-(hydroxymethyl)-1,1-dioxo-2,3-dihydro-1lambda6,2,4-benzothiadiazine-7-sulfonamide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Hydrochlorothiazide, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N4-Hydroxymethyl Hydrochlorothiazide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Hydrochlorothiazide

View every impurity, metabolite and intermediate we list for Hydrochlorothiazide.

Hydrochlorothiazide impurities

Specifications & identifiers

Chemical identifiers
Product name	N4-Hydroxymethyl Hydrochlorothiazide
Catalogue No.	VQ-035284
CAS Number	1216599-78-8
IUPAC name	6-chloro-4-(hydroxymethyl)-1,1-dioxo-2,3-dihydro-1lambda6,2,4-benzothiadiazine-7-sulfonamide
Molecular formula	C₈H₁₀ClN₃O₅S₂
Molecular weight	327.8 g/mol
Exact mass	326.975
Grade	Reference Standard
HSN code	38229090
InChIKey	HPPIFDULMJZMHX-UHFFFAOYSA-N
SMILES	C1NS(=O)(=O)C2=CC(=C(C=C2N1CO)Cl)S(=O)(=O)N
PubChem CID	57369353

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	3 / 8
TPSA	147 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N4-Hydroxymethyl Hydrochlorothiazide?

The CAS Registry Number of N4-Hydroxymethyl Hydrochlorothiazide is 1216599-78-8.

What is the molecular formula and molecular weight of N4-Hydroxymethyl Hydrochlorothiazide?

N4-Hydroxymethyl Hydrochlorothiazide has the molecular formula C8H10ClN3O5S2 and a molecular weight of 327.8 g/mol. Its IUPAC name is 6-chloro-4-(hydroxymethyl)-1,1-dioxo-2,3-dihydro-1lambda6,2,4-benzothiadiazine-7-sulfonamide.

What is N4-Hydroxymethyl Hydrochlorothiazide used for?

N4-Hydroxymethyl Hydrochlorothiazide is supplied as a characterised reference material related to Hydrochlorothiazide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N4-Hydroxymethyl Hydrochlorothiazide can I order?

We supply N4-Hydroxymethyl Hydrochlorothiazide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N4-Hydroxymethyl Hydrochlorothiazide?

Yes. Every lot of N4-Hydroxymethyl Hydrochlorothiazide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N4-Hydroxymethyl Hydrochlorothiazide be shipped internationally?

Yes. We export N4-Hydroxymethyl Hydrochlorothiazide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.