Impurity reference standards
Hydrochlorothiazide impurities & reference standards
Characterised Hydrochlorothiazide impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
34reference materials
2nitrosamine impurities
3isotope-labelled
COAHPLC · NMR · MS on request
Parent API: Hydrochlorothiazide
58-93-5 · C7H8ClN3O4S2
![3,4-Dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide chemical structure](/media/structures/BFUXUGOZJVHVMR-UHFFFAOYSA-N.svg)
3,4-Dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
- CAS
- 23141-82-4
- Formula
- C7H9N3O4S2
- MW
- 263.3 g/mol
VQ-026063
4-Amino-6-chloro-1,3-benzenedisulfonyl Dichloride
- CAS
- 671-89-6
- Formula
- C6H4Cl3NO4S2
- MW
- 324.6 g/mol
VQ-037591
![5-Chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide chemical structure](/media/structures/BLNYGECRDMVABH-UHFFFAOYSA-N.svg)
5-Chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
- CAS
- 856302-12-0
- Formula
- C7H8ClN3O4S2
- MW
- 297.7 g/mol
VQ-026062
![6-Chloro-2H-benzo[e][1,2,3,4]thiatriazine-7-sulfonamide 1,1-dioxide](/media/pack/6-chloro-2h-benzoe1234thiatriazine-7-sulfonamide-11-dioxide.svg?v=3)
6-Chloro-2H-benzo[e][1,2,3,4]thiatriazine-7-sulfonamide 1,1-dioxide
- CAS
- 1214-64-8
- Formula
- C6H5ClN4O4S2
- MW
- 296.7 g/mol
VQ-035265
![6-Chloro-3-oxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide chemical structure](/media/structures/CLWJBTNSDQIMNT-UHFFFAOYSA-N.svg)
6-Chloro-3-oxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
- CAS
- 89813-56-9
- Formula
- C7H6ClN3O5S2
- MW
- 311.7 g/mol
VQ-044148
![6-Chloro-3-styryl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide](/media/pack/6-chloro-3-styryl-34-dihydro-2h-benzoe124thiadiazine-7-sulfonamide-11-dioxide.svg?v=3)
6-Chloro-3-styryl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
- CAS
- 93899-47-9
- Formula
- C15H14ClN3O4S2
- MW
- 399.87 g/mol
VQ-048579
7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide
- CAS
- 22503-74-8
- Formula
- C7H7ClN2O2S
- MW
- 218.66 g/mol
VQ-031081
![7-Methoxy-3-methyl-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide chemical structure](/media/structures/FBBQDXXKORIZQZ-UHFFFAOYSA-N.svg)
7-Methoxy-3-methyl-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
- CAS
- 6451-51-0
- Formula
- C9H10N2O3S
- MW
- 226.25 g/mol
VQ-048578
Diethyl 4-amino-6-chlorobenzene-1,3-disulfonate
- CAS
- 2089381-36-0
- Formula
- C10H14ClNO6S2
- MW
- 343.8 g/mol
VQ-035201
N-((2-Acetamido-5-chlorophenyl)sulfonyl)acetamide
- CAS
- 90794-87-9
- Formula
- C10H11ClN2O4S
- MW
- 290.72 g/mol
VQ-035202
FAQs — Hydrochlorothiazide impurities
Which Hydrochlorothiazide impurities do you supply?
We list 34 Hydrochlorothiazide-related reference materials, including process impurities, degradation products, nitrosamine impurities, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Hydrochlorothiazide impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Hydrochlorothiazide impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
Request Hydrochlorothiazide impurity standards
We reply within one business day with price, pack options, lead time and documentation.