N-Nitrosopyrrolidine D8

About N-Nitrosopyrrolidine D8

N-Nitrosopyrrolidine D8 is a stable isotope labelled analogue related to Valsartan carrying the CAS registry number 1219802-09-1. With the molecular formula C4H8N2O, it has a molar mass of 108.17 g/mol. Systematically, it is named 2,2,3,3,4,4,5,5-octadeuterio-1-nitrosopyrrolidine. Common synonyms include 1-Nitrosopyrrolidine-d8 and 1-nitrosopyrrolidine-2,2,3,3,4,4,5,5-d8.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Nitrosopyrrolidine D8 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	N-Nitrosopyrrolidine D8
Catalogue No.	VQ-042815
CAS Number	1219802-09-1
IUPAC name	2,2,3,3,4,4,5,5-octadeuterio-1-nitrosopyrrolidine
Molecular formula	C₄H₈N₂O
Molecular weight	108.17 g/mol
Exact mass	108.1139
Grade	Reference Standard
HSN code	38229090
InChIKey	WNYADZVDBIBLJJ-SVYQBANQSA-N
SMILES	[2H]C1(C(C(N(C1([2H])[2H])N=O)([2H])[2H])([2H])[2H])[2H]
PubChem CID	87065833

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	0 / 3
TPSA	32.7 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H351Suspected of causing cancer

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitrosopyrrolidine D8?

The CAS Registry Number of N-Nitrosopyrrolidine D8 is 1219802-09-1. It is also known as 1-Nitrosopyrrolidine-d8, 1-nitrosopyrrolidine-2,2,3,3,4,4,5,5-d8.

What is the molecular formula and molecular weight of N-Nitrosopyrrolidine D8?

N-Nitrosopyrrolidine D8 has the molecular formula C4H8N2O and a molecular weight of 108.17 g/mol. Its IUPAC name is 2,2,3,3,4,4,5,5-octadeuterio-1-nitrosopyrrolidine.

What is N-Nitrosopyrrolidine D8 used for?

N-Nitrosopyrrolidine D8 is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitrosopyrrolidine D8 can I order?

We supply N-Nitrosopyrrolidine D8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitrosopyrrolidine D8?

Yes. Every lot of N-Nitrosopyrrolidine D8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitrosopyrrolidine D8 be shipped internationally?

Yes. N-Nitrosopyrrolidine D8 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.