4,4-Difluorocyclohexanecarboxylic acid

Name: 4,4-Difluorocyclohexanecarboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-031724

About 4,4-Difluorocyclohexanecarboxylic acid

Listed under CAS 122665-97-8, 4,4-Difluorocyclohexanecarboxylic acid is an impurity of Maraviroc available from Vaqora Chemicals. With the molecular formula C7H10F2O2, it has a molar mass of 164.15 g/mol. Its systematic (IUPAC) name is 4,4-difluorocyclohexane-1-carboxylic acid. Common synonyms include cyclohexanecarboxylic acid, 4,4-difluoro- and 4,4-difluorocyclohexanoic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Maraviroc to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 4,4-Difluorocyclohexanecarboxylic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Maraviroc

View every impurity, metabolite and intermediate we list for Maraviroc.

Maraviroc impurities

Specifications & identifiers

Chemical identifiers
Product name	4,4-Difluorocyclohexanecarboxylic acid
Catalogue No.	VQ-031724
CAS Number	122665-97-8
IUPAC name	4,4-difluorocyclohexane-1-carboxylic acid
Molecular formula	C₇H₁₀F₂O₂
Molecular weight	164.15 g/mol
Exact mass	164.0649
Grade	Reference Standard
HSN code	38229090
InChIKey	HYIUDFLDFSIXTR-UHFFFAOYSA-N
SMILES	C1CC(CCC1C(=O)O)(F)F
PubChem CID	2779136

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 4
TPSA	37.3 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,4-Difluorocyclohexanecarboxylic acid?

The CAS Registry Number of 4,4-Difluorocyclohexanecarboxylic acid is 122665-97-8. It is also known as cyclohexanecarboxylic acid, 4,4-difluoro-, 4,4-difluorocyclohexanoic acid, 4,4-Difluorocyclohexylcarboxylic acid.

What is the molecular formula and molecular weight of 4,4-Difluorocyclohexanecarboxylic acid?

4,4-Difluorocyclohexanecarboxylic acid has the molecular formula C7H10F2O2 and a molecular weight of 164.15 g/mol. Its IUPAC name is 4,4-difluorocyclohexane-1-carboxylic acid.

What is 4,4-Difluorocyclohexanecarboxylic acid used for?

4,4-Difluorocyclohexanecarboxylic acid is supplied as a characterised reference material related to Maraviroc. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,4-Difluorocyclohexanecarboxylic acid can I order?

We supply 4,4-Difluorocyclohexanecarboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,4-Difluorocyclohexanecarboxylic acid?

Yes. Every lot of 4,4-Difluorocyclohexanecarboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,4-Difluorocyclohexanecarboxylic acid be shipped internationally?

Yes. 4,4-Difluorocyclohexanecarboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.