Gefitinib-d6

Name: Gefitinib-d6
Brand: Vaqora Chemicals
SKU: VQ-037495

About Gefitinib-d6

Gefitinib-d6 (CAS 1228664-49-0) is a stable isotope labelled analogue related to Gefitinib offered by Vaqora Chemicals. Formula C22H24ClFN4O3, molecular weight 452.9 g/mol. Its systematic (IUPAC) name is N-(3-chloro-4-fluorophenyl)-6-(1,1,2,2,3,3-hexadeuterio-3-morpholin-4-ylpropoxy)-7-methoxyquinazolin-4-amine. Common synonyms include TMIJ-0147.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Gefitinib-d6 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Gefitinib

View every impurity, metabolite and intermediate we list for Gefitinib.

Gefitinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Gefitinib-d6
Catalogue No.	VQ-037495
CAS Number	1228664-49-0
IUPAC name	N-(3-chloro-4-fluorophenyl)-6-(1,1,2,2,3,3-hexadeuterio-3-morpholin-4-ylpropoxy)-7-methoxyquinazolin-4-amine
Molecular formula	C₂₂H₂₄ClFN₄O₃
Molecular weight	452.9 g/mol
Exact mass	452.1898
Grade	Reference Standard
HSN code	38229090
InChIKey	XGALLCVXEZPNRQ-AQCDAZAYSA-N
SMILES	[2H]C([2H])(C([2H])([2H])N1CCOCC1)C([2H])([2H])OC2=C(C=C3C(=C2)C(=NC=N3)NC4=CC(=C(C=C4)F)Cl)OC
PubChem CID	46243754

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 8
TPSA	68.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Gefitinib-d6?

The CAS Registry Number of Gefitinib-d6 is 1228664-49-0. It is also known as TMIJ-0147.

What is the molecular formula and molecular weight of Gefitinib-d6?

Gefitinib-d6 has the molecular formula C22H24ClFN4O3 and a molecular weight of 452.9 g/mol. Its IUPAC name is N-(3-chloro-4-fluorophenyl)-6-(1,1,2,2,3,3-hexadeuterio-3-morpholin-4-ylpropoxy)-7-methoxyquinazolin-4-amine.

What is Gefitinib-d6 used for?

Gefitinib-d6 is supplied as a characterised reference material related to Gefitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Gefitinib-d6 can I order?

We supply Gefitinib-d6 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gefitinib-d6?

Yes. Every lot of Gefitinib-d6 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gefitinib-d6 be shipped internationally?

Yes. We export Gefitinib-d6 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.