3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)… 1228779-96-1

Name: 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide
Brand: Vaqora Chemicals
SKU: VQ-013031

About 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide

Vaqora Chemicals supplies 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide, a process intermediate or related compound of Venetoclax registered under CAS number 1228779-96-1. Formula C12H17N3O5S, molecular weight 315.35 g/mol. Systematically, it is named 3-nitro-4-(oxan-4-ylmethylamino)benzenesulfonamide. Common synonyms include no)benzenesulfonaMide and 3-nitro-4-[(oxan-4-ylmethyl).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Venetoclax, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Venetoclax

View every impurity, metabolite and intermediate we list for Venetoclax.

Venetoclax impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide
Catalogue No.	VQ-013031
CAS Number	1228779-96-1
IUPAC name	3-nitro-4-(oxan-4-ylmethylamino)benzenesulfonamide
Molecular formula	C₁₂H₁₇N₃O₅S
Molecular weight	315.35 g/mol
Exact mass	315.0889
Grade	Reference Standard
HSN code	2933
InChIKey	HNQRHNYBVWICKB-UHFFFAOYSA-N
SMILES	C1COCCC1CNC2=C(C=C(C=C2)S(=O)(=O)N)[N+](=O)[O-]
PubChem CID	57474953

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	2 / 7
TPSA	136 Å²
Synonyms	3-Nitro-4-[[(tetrahydropyran-4-yl)methyl]amino]benzenesulfonamide, Benzenesulfonamide, 3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]-, 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl) methyl)amino) benzene sulfonamide, 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl) methyl) amino)benzenesulfonamide, Benzenesulfonamide, 3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)-, 3-nitro-4-((tetrahydro-2H-pyran-4-yl)methylamino)benzenesulfonamide, 3-nitro-4-[(oxan-4-ylmethyl)amino]benzene-1-sulfonamide, 3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]Benzenesulfonamide, 3-?Nitro-?4-?(((tetrahydro-?2H-?pyran-?4-?yl)?methyl)?amino)?benzenesulfonamide, no)benzenesulfonaMide, 3-nitro-4-[(oxan-4-ylmethyl), 3-nitro-4-(tetrahydropyran-4-ylmethylamino)benzenesulfonamide

Safety & hazard information (GHS)

Oxidiser

Environmental hazard

Signal word: Danger

Hazard statements

H272May intensify fire, oxidizer
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P210, P220, P273, P280, P370 + P378, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide?

The CAS Registry Number of 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide is 1228779-96-1. It is also known as 3-Nitro-4-[[(tetrahydropyran-4-yl)methyl]amino]benzenesulfonamide, Benzenesulfonamide, 3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]-, 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl) methyl)amino) benzene sulfonamide.

What is the molecular formula and molecular weight of 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide?

3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide has the molecular formula C12H17N3O5S and a molecular weight of 315.35 g/mol. Its IUPAC name is 3-nitro-4-(oxan-4-ylmethylamino)benzenesulfonamide.

What is 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide used for?

3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide is supplied as a characterised reference material related to Venetoclax. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide can I order?

We supply 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide?

Yes. Every lot of 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide be shipped internationally?

Yes. 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.