9-Norketo FK-506

About 9-Norketo FK-506

9-Norketo FK-506 is an impurity of Tacrolimus carrying the CAS registry number 123719-19-7. The compound has the formula C43H69NO11, corresponding to a molecular weight of 776.0 g/mol. It is also known as 9-Norketo Tacrolimus.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Tacrolimus, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	9-Norketo FK-506
Catalogue No.	VQ-028179
CAS Number	123719-19-7
IUPAC name	(1R,8S,11S,12R,13S,16R,17E,20S,22S,23R,24R,26R)-1,13-dihydroxy-11-[(E)-1-[(1R,3S,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-22,24-dimethoxy-12,18,20,26-tetramethyl-16-prop-2-enyl-10,27-dioxa-3-azatricyclo[21.3.1.03,8]heptacos-17-ene-2,9,15-trione
Molecular formula	C₄₃H₆₉NO₁₁
Molecular weight	776 g/mol
Exact mass	775.4871
Grade	Reference Standard
HSN code	38229090
InChIKey	RJOVJTTUBQJLEI-SZUBLZBRSA-N
SMILES	C[C@@H]1C[C@@H]([C@@H]2[C@@H](C[C@H]([C@@](O2)(C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@H](C4)OC)O)/C)O)C)OC)OC
PubChem CID	71751219

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	3 / 11
TPSA	161 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 9-Norketo FK-506?

The CAS Registry Number of 9-Norketo FK-506 is 123719-19-7. It is also known as 9-Norketo Tacrolimus.

What is the molecular formula and molecular weight of 9-Norketo FK-506?

9-Norketo FK-506 has the molecular formula C43H69NO11 and a molecular weight of 776 g/mol.

What is 9-Norketo FK-506 used for?

9-Norketo FK-506 is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 9-Norketo FK-506 can I order?

We supply 9-Norketo FK-506 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 9-Norketo FK-506?

Yes. Every lot of 9-Norketo FK-506 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 9-Norketo FK-506 be shipped internationally?

Yes. We export 9-Norketo FK-506 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.