Dihydroxy Etravirine

Name: Dihydroxy Etravirine
Brand: Vaqora Chemicals
SKU: VQ-037157

About Dihydroxy Etravirine

Dihydroxy Etravirine (CAS 1246818-67-6) is an impurity of Etravirine offered by Vaqora Chemicals. Formula C20H15BrN6O3, molecular weight 467.3 g/mol. The IUPAC name is 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-bis(hydroxymethyl)benzonitrile. It is also known as Etravirine metabolite M4 or Dimethylhydroxy etravirine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Etravirine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Dihydroxy Etravirine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Etravirine

View every impurity, metabolite and intermediate we list for Etravirine.

Etravirine impurities

Specifications & identifiers

Chemical identifiers
Product name	Dihydroxy Etravirine
Catalogue No.	VQ-037157
CAS Number	1246818-67-6
IUPAC name	4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-bis(hydroxymethyl)benzonitrile
Molecular formula	C₂₀H₁₅BrN₆O₃
Molecular weight	467.3 g/mol
Exact mass	466.0389
Grade	Reference Standard
HSN code	38229090
InChIKey	NMILEPRAYYVRFB-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C#N)NC2=NC(=C(C(=N2)OC3=C(C=C(C=C3CO)C#N)CO)Br)N
PubChem CID	71316232

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	4 / 9
TPSA	161 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dihydroxy Etravirine?

The CAS Registry Number of Dihydroxy Etravirine is 1246818-67-6. It is also known as Etravirine metabolite M4, Dimethylhydroxy etravirine.

What is the molecular formula and molecular weight of Dihydroxy Etravirine?

Dihydroxy Etravirine has the molecular formula C20H15BrN6O3 and a molecular weight of 467.3 g/mol. Its IUPAC name is 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-bis(hydroxymethyl)benzonitrile.

What is Dihydroxy Etravirine used for?

Dihydroxy Etravirine is supplied as a characterised reference material related to Etravirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dihydroxy Etravirine can I order?

We supply Dihydroxy Etravirine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dihydroxy Etravirine?

Yes. Every lot of Dihydroxy Etravirine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dihydroxy Etravirine be shipped internationally?

Yes. We export Dihydroxy Etravirine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.