Sitagliptin Hydroxy Amide Impurity

Name: Sitagliptin Hydroxy Amide Impurity
Brand: Vaqora Chemicals
SKU: VQ-021345

About Sitagliptin Hydroxy Amide Impurity

Listed under CAS 1253056-01-7, Sitagliptin Hydroxy Amide Impurity is a metabolite or degradation product of Sitagliptin available from Vaqora Chemicals. Formula C16H14F6N4O2, molecular weight 408.3 g/mol. Common synonyms include Sitagliptin alcohol and 3-Hydroxy Sitagliptin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Sitagliptin, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin Hydroxy Amide Impurity
Catalogue No.	VQ-021345
CAS Number	1253056-01-7
IUPAC name	3-hydroxy-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Molecular formula	C₁₆H₁₄F₆N₄O₂
Molecular weight	408.3 g/mol
Exact mass	408.1021
Grade	Reference Standard
HSN code	38229090
InChIKey	GUBAVYYUZMCLIR-UHFFFAOYSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)O
PubChem CID	45110549

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	1 / 10
TPSA	71.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin Hydroxy Amide Impurity?

The CAS Registry Number of Sitagliptin Hydroxy Amide Impurity is 1253056-01-7. It is also known as Sitagliptin alcohol, 3-Hydroxy Sitagliptin, Sitagliptin Impurity 10.

What is the molecular formula and molecular weight of Sitagliptin Hydroxy Amide Impurity?

Sitagliptin Hydroxy Amide Impurity has the molecular formula C16H14F6N4O2 and a molecular weight of 408.3 g/mol. Its IUPAC name is 3-hydroxy-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one.

What is Sitagliptin Hydroxy Amide Impurity used for?

Sitagliptin Hydroxy Amide Impurity is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin Hydroxy Amide Impurity can I order?

We supply Sitagliptin Hydroxy Amide Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin Hydroxy Amide Impurity?

Yes. Every lot of Sitagliptin Hydroxy Amide Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin Hydroxy Amide Impurity be shipped internationally?

Yes. We export Sitagliptin Hydroxy Amide Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.