Alectinib

Name: Alectinib
Brand: Vaqora Chemicals
SKU: VQ-007307

About Alectinib

Alectinib is a high-purity reference standard of Alectinib carrying the CAS registry number 1256580-46-7. Formula C30H34N4O2, molecular weight 482.6 g/mol. The IUPAC name is 9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile. It is also known as AF-802 or AF 802.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Alectinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Alectinib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Alectinib

View every impurity, metabolite and intermediate we list for Alectinib.

Alectinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Alectinib
Catalogue No.	VQ-007307
CAS Number	1256580-46-7
Other CAS	1256589-74-8
IUPAC name	9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
Molecular formula	C₃₀H₃₄N₄O₂
Molecular weight	482.6 g/mol
Exact mass	482.2682
Grade	Reference Standard
HSN code	38229090
InChIKey	KDGFLJKFZUIJMX-UHFFFAOYSA-N
SMILES	CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C
PubChem CID	49806720

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	1 / 5
TPSA	72.4 Å²
Synonyms	AF-802, AF 802, ALK Inhibitor RO5424802, Alectinib (CH5424802), ARQ-761, Alectinib (Standard), Alectinib (USAN/INN), CH5424802(Alectinib), ch 5424802, Alectinib, CH5424802(Alectinib)?, EX-A406

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Alectinib?

The CAS Registry Number of Alectinib is 1256580-46-7. It is also known as AF-802, AF 802, ALK Inhibitor RO5424802.

What is the molecular formula and molecular weight of Alectinib?

Alectinib has the molecular formula C30H34N4O2 and a molecular weight of 482.6 g/mol. Its IUPAC name is 9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile.

What is Alectinib used for?

Alectinib is supplied as a characterised reference material related to Alectinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Alectinib can I order?

We supply Alectinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Alectinib?

Yes. Every lot of Alectinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Alectinib be shipped internationally?

Yes. Alectinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.