Trimetazidine EP Impurity B

Name: Trimetazidine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-028530

About Trimetazidine EP Impurity B

Trimetazidine EP Impurity B (CAS 1257-19-8) is a pharmacopeial impurity of Trimetazidine offered by Vaqora Chemicals. The compound has the formula C24H34N2O6, corresponding to a molecular weight of 446.5 g/mol. Its systematic (IUPAC) name is 1,4-bis[(2,3,4-trimethoxyphenyl)methyl]piperazine. It is also known as Trimetazidine Dihydrochloride - Impurity B or Trimetazidine Impurity B.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Trimetazidine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Trimetazidine

View every impurity, metabolite and intermediate we list for Trimetazidine.

Trimetazidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trimetazidine EP Impurity B
Catalogue No.	VQ-028530
CAS Number	1257-19-8
IUPAC name	1,4-bis[(2,3,4-trimethoxyphenyl)methyl]piperazine
Molecular formula	C₂₄H₃₄N₂O₆
Molecular weight	446.5 g/mol
Exact mass	446.2417
Grade	Reference Standard
HSN code	38229090
InChIKey	SZYPCHFFOGTJQE-UHFFFAOYSA-N
SMILES	COC1=C(C(=C(C=C1)CN2CCN(CC2)CC3=C(C(=C(C=C3)OC)OC)OC)OC)OC
PubChem CID	2873831

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 8
TPSA	61.9 Å²
Synonyms	Trimetazidine Dihydrochloride - Impurity B, Trimetazidine Impurity B, Hexametazidine, 1,4-bis(2,3,4-trimethoxybenzyl)piperazine, 1,4-Bis((2,3,4-trimethoxyphenyl)methyl)piperazine, Piperazine, 1,4-bis((2,3,4-trimethoxyphenyl)methyl)-, Trimetazidine dihydrochloride impurity B

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trimetazidine EP Impurity B?

The CAS Registry Number of Trimetazidine EP Impurity B is 1257-19-8. It is also known as Trimetazidine Dihydrochloride - Impurity B, Trimetazidine Impurity B, Hexametazidine.

What is the molecular formula and molecular weight of Trimetazidine EP Impurity B?

Trimetazidine EP Impurity B has the molecular formula C24H34N2O6 and a molecular weight of 446.5 g/mol. Its IUPAC name is 1,4-bis[(2,3,4-trimethoxyphenyl)methyl]piperazine.

What is Trimetazidine EP Impurity B used for?

Trimetazidine EP Impurity B is supplied as a characterised reference material related to Trimetazidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trimetazidine EP Impurity B can I order?

We supply Trimetazidine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trimetazidine EP Impurity B?

Yes. Every lot of Trimetazidine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trimetazidine EP Impurity B be shipped internationally?

Yes. Trimetazidine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.