Venetoclax-d8

Name: Venetoclax-d8
Brand: Vaqora Chemicals
SKU: VQ-034569

About Venetoclax-d8

Venetoclax-d8 (CAS 1257051-06-1) is a stable isotope labelled analogue related to Venetoclax offered by Vaqora Chemicals. Formula C45H50ClN7O7S, molecular weight 876.5 g/mol. It is also known as TMIH-0594.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Venetoclax and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Venetoclax-d8 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Venetoclax

View every impurity, metabolite and intermediate we list for Venetoclax.

Venetoclax impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Venetoclax-d8
Catalogue No.	VQ-034569
CAS Number	1257051-06-1
IUPAC name	4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Molecular formula	C₄₅H₅₀ClN₇O₇S
Molecular weight	876.5 g/mol
Exact mass	875.3683
Grade	Reference Standard
HSN code	38229090
InChIKey	LQBVNQSMGBZMKD-JYSKPPGCSA-N
SMILES	[2H]C1(C(N(C(C(N1CC2=C(CC(CC2)(C)C)C3=CC=C(C=C3)Cl)([2H])[2H])([2H])[2H])C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)([2H])[2H])[2H]
PubChem CID	131971741

Physical properties
Physical form	Solid
LogP (XLogP3)	8.2
H-bond donors / acceptors	3 / 11
TPSA	183 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Venetoclax-d8?

The CAS Registry Number of Venetoclax-d8 is 1257051-06-1. It is also known as TMIH-0594.

What is the molecular formula and molecular weight of Venetoclax-d8?

Venetoclax-d8 has the molecular formula C45H50ClN7O7S and a molecular weight of 876.5 g/mol.

What is Venetoclax-d8 used for?

Venetoclax-d8 is supplied as a characterised reference material related to Venetoclax. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Venetoclax-d8 can I order?

We supply Venetoclax-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Venetoclax-d8?

Yes. Every lot of Venetoclax-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Venetoclax-d8 be shipped internationally?

Yes. We export Venetoclax-d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.