Capecitabine USP Impurity H

Name: Capecitabine USP Impurity H
Brand: Vaqora Chemicals
SKU: VQ-021977

About Capecitabine USP Impurity H

Capecitabine USP Impurity H (CAS 1262133-66-3) is a pharmacopeial impurity of Capecitabine offered by Vaqora Chemicals. The compound has the formula C20H30FN3O9, corresponding to a molecular weight of 475.5 g/mol. Alternative names: Capecitabine 2-O-BDR Impurity and Capecitabine Impurity 12.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Capecitabine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Capecitabine

View every impurity, metabolite and intermediate we list for Capecitabine.

Capecitabine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Capecitabine USP Impurity H
Catalogue No.	VQ-021977
CAS Number	1262133-66-3
IUPAC name	pentyl N-[1-[(2R,3R,4R,5R)-3-[(2S,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]oxy-4-hydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate
Molecular formula	C₂₀H₃₀FN₃O₉
Molecular weight	475.5 g/mol
Exact mass	475.1966
Grade	Reference Standard
HSN code	38229090
InChIKey	BFJRATXGRKMYFE-YXUPXXBNSA-N
SMILES	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@H]2[C@@H]([C@@H]([C@H](O2)C)O)O[C@H]3[C@@H]([C@@H]([C@H](O3)C)O)O
PubChem CID	71587958

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	4 / 10
TPSA	159 Å²
Synonyms	Capecitabine 2-O-BDR Impurity, 5'-Deoxy-2'-O-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-N-((pentyloxy)carbonyl)cytidine, Cytidine, 5'-deoxy-2'-O-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-N-((pentyloxy)carbonyl)-, Capecitabine Impurity 12, 2'-O-(5'-Deoxy-b-D-ribofuranosyl) Capecitabine, 2'-O-(5'-Deoxy-beta-D-ribofuranosyl) Capecitabine, 2'-(5'-Deoxy-Beta-D-ribofuranoyl) Capecitabine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H350May cause cancer
H360May damage fertility or the unborn child
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P264, P264 + P265, P273, P280, P302 + P352, P305 + P351 + P338, P318, P321, P332 + P317, P337 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Capecitabine USP Impurity H?

The CAS Registry Number of Capecitabine USP Impurity H is 1262133-66-3. It is also known as Capecitabine 2-O-BDR Impurity, 5'-Deoxy-2'-O-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-N-((pentyloxy)carbonyl)cytidine, Cytidine, 5'-deoxy-2'-O-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-N-((pentyloxy)carbonyl)-.

What is the molecular formula and molecular weight of Capecitabine USP Impurity H?

Capecitabine USP Impurity H has the molecular formula C20H30FN3O9 and a molecular weight of 475.5 g/mol. Its IUPAC name is pentyl N-[1-[(2R,3R,4R,5R)-3-[(2S,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]oxy-4-hydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate.

What is Capecitabine USP Impurity H used for?

Capecitabine USP Impurity H is supplied as a characterised reference material related to Capecitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Capecitabine USP Impurity H can I order?

We supply Capecitabine USP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Capecitabine USP Impurity H?

Yes. Every lot of Capecitabine USP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Capecitabine USP Impurity H be shipped internationally?

Yes. Capecitabine USP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.