2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-y… 1269440-58-5

Name: 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine
Brand: Vaqora Chemicals
SKU: VQ-045091

About 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine

2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine (CAS 1269440-58-5) is an impurity of Encorafenib offered by Vaqora Chemicals. Formula C10H10ClIN4, molecular weight 348.57 g/mol. Its systematic (IUPAC) name is 2-chloro-4-(3-iodo-1-propan-2-ylpyrazol-4-yl)pyrimidine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Encorafenib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Encorafenib

View every impurity, metabolite and intermediate we list for Encorafenib.

Encorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine
Catalogue No.	VQ-045091
CAS Number	1269440-58-5
IUPAC name	2-chloro-4-(3-iodo-1-propan-2-ylpyrazol-4-yl)pyrimidine
Molecular formula	C₁₀H₁₀ClIN₄
Molecular weight	348.57 g/mol
Exact mass	347.9639
Grade	Reference Standard
HSN code	38229090
InChIKey	NVQXUVPDZGMTOH-UHFFFAOYSA-N
SMILES	CC(C)N1C=C(C(=N1)I)C2=NC(=NC=C2)Cl
PubChem CID	51034341

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 3
TPSA	43.6 Å²
Synonyms	2-Chloro-4-[3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]pyrimidine, 2-Chloro-4-(3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl)pyrimidine, PyriMidine, 2-chloro-4-[3-iodo-1-(1-Methylethyl)-1H-pyrazol-4-yl]-, 2-chloro-4-[3-iodo-1-(propan-2-yl)-1H-pyrazol-4-yl]pyrimidine, 2-Chloro-4-(3-iodo-1-isopropyl-4-pyrazolyl)pyrimidine, 2-chloro-4-(3-iodo-1-isopropyl-pyrazol-4-yl)pyrimidine, 2-Chloro-4-[3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]-pyrimi...

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H303May be harmful if swallowed
H317May cause an allergic skin reaction
H401Toxic to aquatic life
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P272, P273, P280, P301 + P317, P302 + P352, P321, P333 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine?

The CAS Registry Number of 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine is 1269440-58-5. It is also known as 2-Chloro-4-[3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]pyrimidine, 2-Chloro-4-(3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl)pyrimidine, PyriMidine, 2-chloro-4-[3-iodo-1-(1-Methylethyl)-1H-pyrazol-4-yl]-.

What is the molecular formula and molecular weight of 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine?

2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine has the molecular formula C10H10ClIN4 and a molecular weight of 348.57 g/mol. Its IUPAC name is 2-chloro-4-(3-iodo-1-propan-2-ylpyrazol-4-yl)pyrimidine.

What is 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine used for?

2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine is supplied as a characterised reference material related to Encorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine can I order?

We supply 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine?

Yes. Every lot of 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine be shipped internationally?

Yes. 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.