Adapalene-d3

Name: Adapalene-d3
Brand: Vaqora Chemicals
SKU: VQ-029031

About Adapalene-d3

Vaqora Chemicals supplies Adapalene-d3, a stable isotope labelled analogue related to Adapalene registered under CAS number 1276433-89-6. Its molecular formula is C28H28O3 and its molecular weight is 415.5 g/mol. Systematically, it is named 6-[3-(1-adamantyl)-4-(trideuteriomethoxy)phenyl]naphthalene-2-carboxylic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 0 hazard statements. Review the Safety Data Sheet before use.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Adapalene and related analytes in bioanalytical, pharmacokinetic and impurity studies. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Adapalene-d3 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Adapalene

View every impurity, metabolite and intermediate we list for Adapalene.

Adapalene impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Adapalene-d3
Catalogue No.	VQ-029031
CAS Number	1276433-89-6
IUPAC name	6-[3-(1-adamantyl)-4-(trideuteriomethoxy)phenyl]naphthalene-2-carboxylic acid
Molecular formula	C₂₈H₂₈O₃
Molecular weight	415.5 g/mol
Exact mass	415.2227
Grade	Reference Standard
HSN code	38229090
InChIKey	LZCDAPDGXCYOEH-FIBGUPNXSA-N
SMILES	[2H]C([2H])([2H])OC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5
PubChem CID	71313023

Physical properties
Physical form	Solid
LogP (XLogP3)	7.7
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Adapalene-d3?

The CAS Registry Number of Adapalene-d3 is 1276433-89-6. It is also known as 6-(3-(1-Adamantyl)-4-(trideuteriomethoxy)phenyl)naphthalene-2-carboxylic acid, 6-(3-((3r,5r,7r)-adamantan-1-yl)-4-(methoxy-d3)phenyl)-2-naphthoic acid.

What is the molecular formula and molecular weight of Adapalene-d3?

Adapalene-d3 has the molecular formula C28H28O3 and a molecular weight of 415.5 g/mol. Its IUPAC name is 6-[3-(1-adamantyl)-4-(trideuteriomethoxy)phenyl]naphthalene-2-carboxylic acid.

What is Adapalene-d3 used for?

Adapalene-d3 is supplied as a characterised reference material related to Adapalene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Adapalene-d3 can I order?

We supply Adapalene-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Adapalene-d3?

Yes. Every lot of Adapalene-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Adapalene-d3 be shipped internationally?

Yes. Adapalene-d3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.