Boc-D-4,4-Biphenylalanine

Name: Boc-D-4,4-Biphenylalanine
Brand: Vaqora Chemicals
SKU: VQ-042063

About Boc-D-4,4-Biphenylalanine

Boc-D-4,4-Biphenylalanine (CAS 128779-47-5) is an impurity of Sacubitril offered by Vaqora Chemicals. Formula C20H23NO4, molecular weight 341.4 g/mol. Its systematic (IUPAC) name is (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoic acid. Common synonyms include Boc-3-(4-Biphenylyl)-D-alanine and N-Boc-3-(4-biphenylyl)-D-alanine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Sacubitril impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Boc-D-4,4-Biphenylalanine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Boc-D-4,4-Biphenylalanine
Catalogue No.	VQ-042063
CAS Number	128779-47-5
IUPAC name	(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoic acid
Molecular formula	C₂₀H₂₃NO₄
Molecular weight	341.4 g/mol
Exact mass	341.1627
Grade	Reference Standard
HSN code	38229090
InChIKey	NBVVKAUSAGHTSU-QGZVFWFLSA-N
SMILES	CC(C)(C)OC(=O)N[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)C(=O)O
PubChem CID	7019133

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²
Synonyms	Boc-3-(4-Biphenylyl)-D-alanine, N-Boc-3-(4-biphenylyl)-D-alanine, [1,1'-Biphenyl]-4-propanoic acid, alpha-[[(1,1-dimethylethoxy)carbonyl]amino]-, (alphaR)-, Boc-D-Bip-OH, (R)-a-(Boc-amino)-biphenyl-4-propanoic acid, (R)-3-([1,1'-Biphenyl]-4-yl)-2-[(tert-butoxycarbonyl)amino]propanoic acid, (2R)-2-(tert-butoxycarbonylamino)-3-(4-phenylphenyl)propanoic acid, (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-phenylphenyl)propanoic acid, (2R)-3-{[1,1'-biphenyl]-4-yl}-2-{[(tert-butoxy)carbonyl]amino}propanoic acid, N-(tert-Butoxycarbonyl)-4-phenyl-D-phenylalanine, (R)-3-biphenyl-4-yl-2-t-butoxycarbonylamino-propionic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Boc-D-4,4-Biphenylalanine?

The CAS Registry Number of Boc-D-4,4-Biphenylalanine is 128779-47-5. It is also known as Boc-3-(4-Biphenylyl)-D-alanine, N-Boc-3-(4-biphenylyl)-D-alanine, [1,1'-Biphenyl]-4-propanoic acid, alpha-[[(1,1-dimethylethoxy)carbonyl]amino]-, (alphaR)-.

What is the molecular formula and molecular weight of Boc-D-4,4-Biphenylalanine?

Boc-D-4,4-Biphenylalanine has the molecular formula C20H23NO4 and a molecular weight of 341.4 g/mol. Its IUPAC name is (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoic acid.

What is Boc-D-4,4-Biphenylalanine used for?

Boc-D-4,4-Biphenylalanine is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Boc-D-4,4-Biphenylalanine can I order?

We supply Boc-D-4,4-Biphenylalanine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Boc-D-4,4-Biphenylalanine?

Yes. Every lot of Boc-D-4,4-Biphenylalanine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Boc-D-4,4-Biphenylalanine be shipped internationally?

Yes. We export Boc-D-4,4-Biphenylalanine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.