Nebivolol B Isomer

About Nebivolol B Isomer

Nebivolol B Isomer is an impurity of Nebivolol carrying the CAS registry number 129050-26-6. The compound has the formula C11H11FO2, corresponding to a molecular weight of 194.2 g/mol. Systematically, it is named (2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene. It is also known as (R)-6-fluoro-2-((R)-oxiran-2-yl)chroman or (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Nebivolol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Nebivolol B Isomer in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	Nebivolol B Isomer
Catalogue No.	VQ-032087
CAS Number	129050-26-6
IUPAC name	(2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene
Molecular formula	C₁₁H₁₁FO₂
Molecular weight	194.2 g/mol
Exact mass	194.0743
Grade	Reference Standard
HSN code	38229090
InChIKey	GVZDIJGBXSDSEP-GHMZBOCLSA-N
SMILES	C1CC2=C(C=CC(=C2)F)O[C@H]1[C@H]3CO3
PubChem CID	11356016

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 3
TPSA	21.8 Å²
Synonyms	(2R)-6-Fluoro-3,4-dihydro-2-((2R)-2-oxiranyl)-2H-1-benzopyran, (2R)-6-Fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-2H-1-benzopyran, (R)-6-fluoro-3,4-dihydro-2-((R)-oxiran-2-yl)-2H-chromene, (2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-chromene, (R)-6-fluoro-2-((R)-oxiran-2-yl)chroman, (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane, 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-(2R)-2-oxiranyl-, (2R)-rel-, (R)-6-Fluoro-2-((R)-oxiran-2-yl)chromane, (2R)-6-Fluoro-2-[(2R)-2-oxiranyl]chromane, (2R)-6-Fluoro-2-[(2S)-2-oxiranyl]chromane, rel-(R)-6-Fluoro-2-((R)-oxiran-2-yl)chromane, (R)-6-fluoro-3,4-dihydro((R)-oxiran-2-yl)-2H-chromen

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nebivolol B Isomer?

The CAS Registry Number of Nebivolol B Isomer is 129050-26-6. It is also known as (2R)-6-Fluoro-3,4-dihydro-2-((2R)-2-oxiranyl)-2H-1-benzopyran, (2R)-6-Fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-2H-1-benzopyran, (R)-6-fluoro-3,4-dihydro-2-((R)-oxiran-2-yl)-2H-chromene.

What is the molecular formula and molecular weight of Nebivolol B Isomer?

Nebivolol B Isomer has the molecular formula C11H11FO2 and a molecular weight of 194.2 g/mol. Its IUPAC name is (2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene.

What is Nebivolol B Isomer used for?

Nebivolol B Isomer is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nebivolol B Isomer can I order?

We supply Nebivolol B Isomer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nebivolol B Isomer?

Yes. Every lot of Nebivolol B Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nebivolol B Isomer be shipped internationally?

Yes. We export Nebivolol B Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.