Ezetimibe Tetrahydropyran Impurity

About Ezetimibe Tetrahydropyran Impurity

Ezetimibe Tetrahydropyran Impurity is a metabolite or degradation product of Ezetimibe carrying the CAS registry number 1296129-15-1. With the molecular formula C24H21F2NO3, it has a molar mass of 409.4 g/mol. Systematically, it is named (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)oxane-3-carboxamide. Alternative names: Ezetimibe Tetrahydropyran Analog and Ezetimibe Cyclic Ether Impurity.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Ezetimibe, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Ezetimibe Tetrahydropyran Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Specifications & identifiers

Chemical identifiers
Product name	Ezetimibe Tetrahydropyran Impurity
Catalogue No.	VQ-021224
CAS Number	1296129-15-1
IUPAC name	(2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)oxane-3-carboxamide
Molecular formula	C₂₄H₂₁F₂NO₃
Molecular weight	409.4 g/mol
Exact mass	409.1489
Grade	Reference Standard
HSN code	38229090
InChIKey	IBDXWUJVRNPFPE-VJBWXMMDSA-N
SMILES	C1C[C@H](O[C@H]([C@@H]1C(=O)NC2=CC=C(C=C2)F)C3=CC=C(C=C3)O)C4=CC=C(C=C4)F
PubChem CID	71316708

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 5
TPSA	58.6 Å²
Synonyms	Ezetimibe Tetrahydropyran Analog, Ezetimibe Cyclic Ether Impurity, (2R,3R,6S)-N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide, (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide, Ezetimibe Impurity 17(SCH59566), Ezetimibe Impurity 36(Tetrahydropyran Impurity), 2H-Pyran-3-carboxamide, N,6-bis(4-fluorophenyl)tetra, N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran- 3-carboxamide, N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide, (2R,3R,6S)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ezetimibe Tetrahydropyran Impurity?

The CAS Registry Number of Ezetimibe Tetrahydropyran Impurity is 1296129-15-1. It is also known as Ezetimibe Tetrahydropyran Analog, Ezetimibe Cyclic Ether Impurity, (2R,3R,6S)-N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide.

What is the molecular formula and molecular weight of Ezetimibe Tetrahydropyran Impurity?

Ezetimibe Tetrahydropyran Impurity has the molecular formula C24H21F2NO3 and a molecular weight of 409.4 g/mol. Its IUPAC name is (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)oxane-3-carboxamide.

What is Ezetimibe Tetrahydropyran Impurity used for?

Ezetimibe Tetrahydropyran Impurity is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ezetimibe Tetrahydropyran Impurity can I order?

We supply Ezetimibe Tetrahydropyran Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ezetimibe Tetrahydropyran Impurity?

Yes. Every lot of Ezetimibe Tetrahydropyran Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ezetimibe Tetrahydropyran Impurity be shipped internationally?

Yes. We export Ezetimibe Tetrahydropyran Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.