Buprenorphine EP Impurity E

About Buprenorphine EP Impurity E

Buprenorphine EP Impurity E is a pharmacopeial impurity of Buprenorphine carrying the CAS registry number 130668-48-3. Formula C28H39NO4, molecular weight 453.6 g/mol. Common synonyms include Buprenorphine - Impurity E (PSY) and 6-O-Desmethyl Buprenorphine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Buprenorphine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Buprenorphine EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Buprenorphine

View every impurity, metabolite and intermediate we list for Buprenorphine.

Buprenorphine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Buprenorphine EP Impurity E
Catalogue No.	VQ-035516
CAS Number	130668-48-3
IUPAC name	(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene-11,15-diol
Molecular formula	C₂₈H₃₉NO₄
Molecular weight	453.6 g/mol
Exact mass	453.2879
Grade	Reference Standard
HSN code	38229090
InChIKey	PVQDTNRTSUTFFF-JOJQJKSDSA-N
SMILES	C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)O)(C(C)(C)C)O
PubChem CID	14748550

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	3 / 5
TPSA	73.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Buprenorphine EP Impurity E?

The CAS Registry Number of Buprenorphine EP Impurity E is 130668-48-3. It is also known as Buprenorphine - Impurity E (PSY), 6-O-Desmethyl Buprenorphine, Desmethyl Buprenorphine.

What is the molecular formula and molecular weight of Buprenorphine EP Impurity E?

Buprenorphine EP Impurity E has the molecular formula C28H39NO4 and a molecular weight of 453.6 g/mol.

What is Buprenorphine EP Impurity E used for?

Buprenorphine EP Impurity E is supplied as a characterised reference material related to Buprenorphine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Buprenorphine EP Impurity E can I order?

We supply Buprenorphine EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Buprenorphine EP Impurity E?

Yes. Every lot of Buprenorphine EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Buprenorphine EP Impurity E be shipped internationally?

Yes. We export Buprenorphine EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.