All-trans 5,6-Epoxy Retinoic Acid

Name: All-trans 5,6-Epoxy Retinoic Acid
Brand: Vaqora Chemicals
SKU: VQ-031286

About All-trans 5,6-Epoxy Retinoic Acid

Listed under CAS 13100-69-1, All-trans 5,6-Epoxy Retinoic Acid is a metabolite or degradation product of Isotretinoin available from Vaqora Chemicals. With the molecular formula C20H28O3, it has a molar mass of 316.4 g/mol. The IUPAC name is (2E,4E,6E,8E)-3,7-dimethyl-9-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)nona-2,4,6,8-tetraenoic acid. It is also known as 6-Epoxy-Retinoic Acid or 5,6-Epoxyretinoic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Isotretinoin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	All-trans 5,6-Epoxy Retinoic Acid
Catalogue No.	VQ-031286
CAS Number	13100-69-1
IUPAC name	(2E,4E,6E,8E)-3,7-dimethyl-9-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)nona-2,4,6,8-tetraenoic acid
Molecular formula	C₂₀H₂₈O₃
Molecular weight	316.4 g/mol
Exact mass	316.2038
Grade	Reference Standard
HSN code	38229090
InChIKey	KEEHJLBAOLGBJZ-WEDZBJJJSA-N
SMILES	C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C12C(CCCC1(O2)C)(C)C
PubChem CID	5363137

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	1 / 3
TPSA	49.8 Å²
Synonyms	6-Epoxy-Retinoic Acid, 5,6-Epoxyretinoic acid, all-trans-5,6-Epoxy-5,6-dihydroretinoic acid, 5,6-Epoxy-5,6-dihydroretinoic Acid, 9-cis-5,6-Epoxy-5,6-dihydro-retinoic Acid, 5,6-Epoxyretinoicacid, 5,6-epoxy-5,6-dihydro-Retinoate, 5,6-epoxy-5,6-dihydro-Retinoic acid, all-trans-5,6-Epoxy-5,6-dihydroretinoate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of All-trans 5,6-Epoxy Retinoic Acid?

The CAS Registry Number of All-trans 5,6-Epoxy Retinoic Acid is 13100-69-1. It is also known as 6-Epoxy-Retinoic Acid, 5,6-Epoxyretinoic acid, all-trans-5,6-Epoxy-5,6-dihydroretinoic acid.

What is the molecular formula and molecular weight of All-trans 5,6-Epoxy Retinoic Acid?

All-trans 5,6-Epoxy Retinoic Acid has the molecular formula C20H28O3 and a molecular weight of 316.4 g/mol. Its IUPAC name is (2E,4E,6E,8E)-3,7-dimethyl-9-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)nona-2,4,6,8-tetraenoic acid.

What is All-trans 5,6-Epoxy Retinoic Acid used for?

All-trans 5,6-Epoxy Retinoic Acid is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of All-trans 5,6-Epoxy Retinoic Acid can I order?

We supply All-trans 5,6-Epoxy Retinoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with All-trans 5,6-Epoxy Retinoic Acid?

Yes. Every lot of All-trans 5,6-Epoxy Retinoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can All-trans 5,6-Epoxy Retinoic Acid be shipped internationally?

Yes. All-trans 5,6-Epoxy Retinoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.