Lamivudine EP Impurity B

Name: Lamivudine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-006451

About Lamivudine EP Impurity B

Listed under CAS 131086-22-1, Lamivudine EP Impurity B is a pharmacopeial impurity of Lamivudine available from Vaqora Chemicals. The compound has the formula C8H11N3O3S, corresponding to a molecular weight of 229.26 g/mol. Systematically, it is named 4-amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one. It is also known as (±)-trans-Lamivudine or Lamivudine, (+-)-trans-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Lamivudine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Lamivudine

View every impurity, metabolite and intermediate we list for Lamivudine.

Lamivudine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Lamivudine EP Impurity B
Catalogue No.	VQ-006451
CAS Number	131086-22-1
IUPAC name	4-amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Molecular formula	C₈H₁₁N₃O₃S
Molecular weight	229.26 g/mol
Exact mass	229.0521
Grade	Reference Standard
HSN code	38229090
InChIKey	JTEGQNOMFQHVDC-BQBZGAKWSA-N
SMILES	C1[C@H](O[C@@H](S1)CO)N2C=CC(=NC2=O)N
PubChem CID	6540852

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	2 / 4
TPSA	113 Å²
Synonyms	4-Amino-1-[(2RS,5RS)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one, (±)-trans-Lamivudine, 2(1H)-Pyrimidinone, 4-amino-1-((2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, rel-, 2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, trans-, Lamivudine, (+-)-trans-, Lamivudine, (A+-)-trans-, Lamivudine, (+/-)-trans-, 2'-Epi-Lamivudine, (+/-)-trans-Lamivudine, 4-Amino-1-((2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one, 4-Amino-1-((2RS,5RS)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lamivudine EP Impurity B?

The CAS Registry Number of Lamivudine EP Impurity B is 131086-22-1. It is also known as 4-Amino-1-[(2RS,5RS)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one, (±)-trans-Lamivudine.

What is the molecular formula and molecular weight of Lamivudine EP Impurity B?

Lamivudine EP Impurity B has the molecular formula C8H11N3O3S and a molecular weight of 229.26 g/mol. Its IUPAC name is 4-amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.

What is Lamivudine EP Impurity B used for?

Lamivudine EP Impurity B is supplied as a characterised reference material related to Lamivudine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lamivudine EP Impurity B can I order?

We supply Lamivudine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lamivudine EP Impurity B?

Yes. Every lot of Lamivudine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lamivudine EP Impurity B be shipped internationally?

Yes. We export Lamivudine EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.