Budesonide EP Impurity E

Name: Budesonide EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-020996

About Budesonide EP Impurity E

Vaqora Chemicals supplies Budesonide EP Impurity E, a pharmacopeial impurity of Budesonide registered under CAS number 131918-64-4. The compound has the formula C25H32O6, corresponding to a molecular weight of 428.5 g/mol. It is also known as Budesonide - Impurity E or Budesonide 14-ene.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Budesonide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Budesonide EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Budesonide

View every impurity, metabolite and intermediate we list for Budesonide.

Budesonide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Budesonide EP Impurity E
Catalogue No.	VQ-020996
CAS Number	131918-64-4
IUPAC name	(1R,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-2,14,17-trien-16-one
Molecular formula	C₂₅H₃₂O₆
Molecular weight	428.5 g/mol
Exact mass	428.2199
Grade	Reference Standard
HSN code	38229090
InChIKey	PMZXYZGZQZYDLA-BQKXZEBKSA-N
SMILES	CCCC1O[C@@H]2C=C3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C
PubChem CID	12989325

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 6
TPSA	93.1 Å²
Synonyms	Budesonide - Impurity E, Budesonide 14-ene, 14,15-Dehydrobudesonide, (11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4,14-triene-3,20-dione, 16alpha,17-(Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4,14-triene-3,20-dione, 16alpha,17-[butylidenebis(oxy)]-11beta,21-dihydroxypregna-1,4,14-triene-3,20-dione, 14,15-Dehydro Budesonide, (11beta,16beta)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4,14-triene-3,20-dione

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H372Causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Budesonide EP Impurity E?

The CAS Registry Number of Budesonide EP Impurity E is 131918-64-4. It is also known as Budesonide - Impurity E, Budesonide 14-ene, 14,15-Dehydrobudesonide.

What is the molecular formula and molecular weight of Budesonide EP Impurity E?

Budesonide EP Impurity E has the molecular formula C25H32O6 and a molecular weight of 428.5 g/mol. Its IUPAC name is (1R,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-2,14,17-trien-16-one.

What is Budesonide EP Impurity E used for?

Budesonide EP Impurity E is supplied as a characterised reference material related to Budesonide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Budesonide EP Impurity E can I order?

We supply Budesonide EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Budesonide EP Impurity E?

Yes. Every lot of Budesonide EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Budesonide EP Impurity E be shipped internationally?

Yes. Budesonide EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.