N-Nitrososarcosine

Name: N-Nitrososarcosine
Brand: Vaqora Chemicals
SKU: VQ-023390

About N-Nitrososarcosine

N-Nitrososarcosine (CAS 13256-22-9) is a nitrosamine impurity of Sarcosine offered by Vaqora Chemicals. The compound has the formula C3H6N2O3, corresponding to a molecular weight of 118.09 g/mol. The IUPAC name is 2-[methyl(nitroso)amino]acetic acid. Common synonyms include N-Methyl-N-nitrosoglycine and N-Nitrosomethylglycine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Sarcosine, method validation (AMV) and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Nitrososarcosine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Sarcosine

View every impurity, metabolite and intermediate we list for Sarcosine.

Sarcosine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitrososarcosine
Catalogue No.	VQ-023390
CAS Number	13256-22-9
IUPAC name	2-[methyl(nitroso)amino]acetic acid
Molecular formula	C₃H₆N₂O₃
Molecular weight	118.09 g/mol
Exact mass	118.0378
Grade	Reference Standard
HSN code	38229090
InChIKey	HJMPSKKJHVWPBK-UHFFFAOYSA-N
SMILES	CN(CC(=O)O)N=O
PubChem CID	25811

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	1 / 5
TPSA	70 Å²
Synonyms	N-Methyl-N-nitrosoglycine, N-Nitrosomethylglycine, Nitroso sarkosin, Glycine, N-methyl-N-nitroso-, Sarcosine, N-nitroso-, N-Methyl-N-(carboxymethyl)nitrosamine, Acetic acid, 2-(methylnitrosoamino)-, N-Methyl-N-Nitroso-Glycine, [methyl(nitroso)amino]acetic acid, 2-(methyl(nitroso)amino)acetic acid, 2-(Methylnitrosoamino)acetic Acid

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitrososarcosine?

The CAS Registry Number of N-Nitrososarcosine is 13256-22-9. It is also known as N-Methyl-N-nitrosoglycine, N-Nitrosomethylglycine, Nitroso sarkosin.

What is the molecular formula and molecular weight of N-Nitrososarcosine?

N-Nitrososarcosine has the molecular formula C3H6N2O3 and a molecular weight of 118.09 g/mol. Its IUPAC name is 2-[methyl(nitroso)amino]acetic acid.

What is N-Nitrososarcosine used for?

N-Nitrososarcosine is supplied as a characterised reference material related to Sarcosine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitrososarcosine can I order?

We supply N-Nitrososarcosine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitrososarcosine?

Yes. Every lot of N-Nitrososarcosine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitrososarcosine be shipped internationally?

Yes. N-Nitrososarcosine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.