Trichlormethiazide
Synonyms: Trichloromethiazide · Metahydrin · Diuroral · Esmarin
Trichlormethiazide (CAS 133-67-5) – API reference standard. C8H8Cl3N3O4S2, MW 380.7. COA included. Worldwide shipping from Vaqora Chemicals.
About Trichlormethiazide
Trichlormethiazide (CAS 133-67-5) is an API reference standard offered by Vaqora Chemicals. Its molecular formula is C8H8Cl3N3O4S2 and its molecular weight is 380.7 g/mol. Its systematic (IUPAC) name is 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide. Alternative names: Trichloromethiazide and Metahydrin.
It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.
Laboratories use this the parent drug substance standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies Trichlormethiazide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.
Typical applications
- Identification & assay
- Method development & validation
- QC reference material
Industries
Specifications & identifiers
| Product name | Trichlormethiazide |
|---|---|
| Catalogue No. | VQ-034425 |
| CAS Number | 133-67-5 |
| IUPAC name | 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide |
| Molecular formula | C8H8Cl3N3O4S2 |
| Molecular weight | 380.7 g/mol |
| Exact mass | 378.9022 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | LMJSLTNSBFUCMU-UHFFFAOYSA-N |
| SMILES | C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)NC(N2)C(Cl)Cl |
| PubChem CID | 5560 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 0.6 |
| H-bond donors / acceptors | 3 / 7 |
| TPSA | 135 Ų |
| Synonyms | Trichloromethiazide, Metahydrin, Diuroral, Esmarin, Gangesol, Hydrotrichlorothiazide, Triclordiuride, Eurinol, Triclormetiazide, Trichloromethiadiazide, Ciba 7057-Su, Trichlordiuride |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H317May cause an allergic skin reactionH334May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statements: P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Trichlormethiazide?
The CAS Registry Number of Trichlormethiazide is 133-67-5. It is also known as Trichloromethiazide, Metahydrin, Diuroral.
What is the molecular formula and molecular weight of Trichlormethiazide?
Trichlormethiazide has the molecular formula C8H8Cl3N3O4S2 and a molecular weight of 380.7 g/mol. Its IUPAC name is 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide.
Which grade and pack sizes of Trichlormethiazide can I order?
We supply Trichlormethiazide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Trichlormethiazide?
Yes. Every lot of Trichlormethiazide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Trichlormethiazide be shipped internationally?
Yes. Trichlormethiazide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Trichlormethiazide
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