N-Desmethyl apalutamide

About N-Desmethyl apalutamide

N-Desmethyl apalutamide is a metabolite or degradation product of Apalutamide carrying the CAS registry number 1332391-11-3. With the molecular formula C20H13F4N5O2S, it has a molar mass of 463.4 g/mol. Common synonyms include Apalutamide metabolite M3.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Apalutamide, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl apalutamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Apalutamide

View every impurity, metabolite and intermediate we list for Apalutamide.

Apalutamide impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl apalutamide
Catalogue No.	VQ-024305
CAS Number	1332391-11-3
IUPAC name	4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluorobenzamide
Molecular formula	C₂₀H₁₃F₄N₅O₂S
Molecular weight	463.4 g/mol
Exact mass	463.0726
Grade	Reference Standard
HSN code	38229090
InChIKey	BAANHOAPFBHUDX-UHFFFAOYSA-N
SMILES	C1CC2(C1)C(=O)N(C(=S)N2C3=CC(=C(C=C3)C(=O)N)F)C4=CC(=C(N=C4)C#N)C(F)(F)F
PubChem CID	86683490

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 9
TPSA	135 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl apalutamide?

The CAS Registry Number of N-Desmethyl apalutamide is 1332391-11-3. It is also known as Apalutamide metabolite M3.

What is the molecular formula and molecular weight of N-Desmethyl apalutamide?

N-Desmethyl apalutamide has the molecular formula C20H13F4N5O2S and a molecular weight of 463.4 g/mol. Its IUPAC name is 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluorobenzamide.

What is N-Desmethyl apalutamide used for?

N-Desmethyl apalutamide is supplied as a characterised reference material related to Apalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl apalutamide can I order?

We supply N-Desmethyl apalutamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl apalutamide?

Yes. Every lot of N-Desmethyl apalutamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl apalutamide be shipped internationally?

Yes. We export N-Desmethyl apalutamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.