Ketoconazole EP Impurity E

Name: Ketoconazole EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-026286

About Ketoconazole EP Impurity E

Vaqora Chemicals supplies Ketoconazole EP Impurity E, a pharmacopeial impurity of Ketoconazole registered under CAS number 134071-44-6. The compound has the formula C21H20Cl2N2O5S, corresponding to a molecular weight of 483.4 g/mol. Systematically, it is named [(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate. Common synonyms include Ketoconazole Impurity E and Ketoconazole - Impurity E.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Ketoconazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ketoconazole EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ketoconazole

View every impurity, metabolite and intermediate we list for Ketoconazole.

Ketoconazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ketoconazole EP Impurity E
Catalogue No.	VQ-026286
CAS Number	134071-44-6
IUPAC name	[(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate
Molecular formula	C₂₁H₂₀Cl₂N₂O₅S
Molecular weight	483.4 g/mol
Exact mass	482.047
Grade	Reference Standard
HSN code	38229090
InChIKey	WAXNIYHZFWRPGS-UTKZUKDTSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)OC[C@H]2CO[C@](O2)(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl
PubChem CID	10814675

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	0 / 6
TPSA	88 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ketoconazole EP Impurity E?

The CAS Registry Number of Ketoconazole EP Impurity E is 134071-44-6. It is also known as Ketoconazole Impurity E, Ketoconazole - Impurity E, Ketoconazole Impurity 10.

What is the molecular formula and molecular weight of Ketoconazole EP Impurity E?

Ketoconazole EP Impurity E has the molecular formula C21H20Cl2N2O5S and a molecular weight of 483.4 g/mol. Its IUPAC name is [(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate.

What is Ketoconazole EP Impurity E used for?

Ketoconazole EP Impurity E is supplied as a characterised reference material related to Ketoconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketoconazole EP Impurity E can I order?

We supply Ketoconazole EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketoconazole EP Impurity E?

Yes. Every lot of Ketoconazole EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketoconazole EP Impurity E be shipped internationally?

Yes. We export Ketoconazole EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.