Domperidone EP Impurity B

Name: Domperidone EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-025363

About Domperidone EP Impurity B

Domperidone EP Impurity B (CAS 1346598-11-5) is a pharmacopeial impurity of Domperidone offered by Vaqora Chemicals. With the molecular formula C13H14ClN3O2, it has a molar mass of 279.72 g/mol. Its systematic (IUPAC) name is 4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidine-1-carbaldehyde. It is also known as Domperidone - Impurity B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Domperidone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Domperidone EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Domperidone

View every impurity, metabolite and intermediate we list for Domperidone.

Domperidone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Domperidone EP Impurity B
Catalogue No.	VQ-025363
CAS Number	1346598-11-5
IUPAC name	4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidine-1-carbaldehyde
Molecular formula	C₁₃H₁₄ClN₃O₂
Molecular weight	279.72 g/mol
Exact mass	279.0775
Grade	Reference Standard
HSN code	38229090
InChIKey	KVXFJSQPTDUFPA-UHFFFAOYSA-N
SMILES	C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)C=O
PubChem CID	71314765

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 2
TPSA	52.7 Å²
Synonyms	Domperidone - Impurity B, 4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-formylpiperidine, 1-Piperidinecarboxaldehyde, 4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-, 4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinecarboxaldehyde, 4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-1-carbaldehyde, 4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-1-piperidinecarbaldehyde

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Domperidone EP Impurity B?

The CAS Registry Number of Domperidone EP Impurity B is 1346598-11-5. It is also known as Domperidone - Impurity B, 4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-formylpiperidine, 1-Piperidinecarboxaldehyde, 4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-.

What is the molecular formula and molecular weight of Domperidone EP Impurity B?

Domperidone EP Impurity B has the molecular formula C13H14ClN3O2 and a molecular weight of 279.72 g/mol. Its IUPAC name is 4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidine-1-carbaldehyde.

What is Domperidone EP Impurity B used for?

Domperidone EP Impurity B is supplied as a characterised reference material related to Domperidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Domperidone EP Impurity B can I order?

We supply Domperidone EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Domperidone EP Impurity B?

Yes. Every lot of Domperidone EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Domperidone EP Impurity B be shipped internationally?

Yes. Domperidone EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.