(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine 1354621-59-2

Name: (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
Brand: Vaqora Chemicals
SKU: VQ-012758

About (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine

(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine (CAS 1354621-59-2) is a process intermediate or related compound of Tofacitinib offered by Vaqora Chemicals. With the molecular formula C14H22N2, it has a molar mass of 218.34 g/mol. Alternative names: cis-1-Benzyl-N,4-dimethylpiperidin-3-amine and 1-Benzyl-N,4-dimethylpiperidin-3-amine, cis-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Tofacitinib, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
Catalogue No.	VQ-012758
CAS Number	1354621-59-2
Other CAS	1354486-07-9
IUPAC name	(3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
Molecular formula	C₁₄H₂₂N₂
Molecular weight	218.34 g/mol
Exact mass	218.1783
Grade	Reference Standard
HSN code	2933
InChIKey	NVKDDQBZODSEIN-GXTWGEPZSA-N
SMILES	C[C@H]1CCN(C[C@H]1NC)CC2=CC=CC=C2
PubChem CID	44630605

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 2
TPSA	15.3 Å²
Synonyms	(3S,4S)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine, cis-1-Benzyl-N,4-dimethylpiperidin-3-amine, rel-((3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine), (3S,4S)-1-Benzyl-N,4-dimethyl-3-piperidinamine, 1-Benzyl-N,4-dimethylpiperidin-3-amine, cis-, cis-1-Benzyl-3-(methylamino)-4-methylpiperidine, (3S,4S)-1-benzyl-N,4-dimethyl-piperidin-3-amine, 1-Benzyl-N,4-dimethylpiperidin-3-amine, (3S,4S)-, (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine, AldrichCPR, 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3S,4S)-, rel-(3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine?

The CAS Registry Number of (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is 1354621-59-2. It is also known as (3S,4S)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine, cis-1-Benzyl-N,4-dimethylpiperidin-3-amine, rel-((3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine).

What is the molecular formula and molecular weight of (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine?

(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine has the molecular formula C14H22N2 and a molecular weight of 218.34 g/mol. Its IUPAC name is (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine.

What is (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine used for?

(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine can I order?

We supply (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine?

Yes. Every lot of (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine be shipped internationally?

Yes. (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.