5-(Methyl-d3)tetrahydrofolic acid

Name: 5-(Methyl-d3)tetrahydrofolic acid
Brand: Vaqora Chemicals
SKU: VQ-030862

About 5-(Methyl-d3)tetrahydrofolic acid

5-(Methyl-d3)tetrahydrofolic acid is a stable isotope labelled analogue related to Folic Acid carrying the CAS registry number 1356019-97-0. Formula C20H25N7O6, molecular weight 462.5 g/mol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Folic Acid and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-(Methyl-d3)tetrahydrofolic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Folic Acid

View every impurity, metabolite and intermediate we list for Folic Acid.

Folic Acid impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	5-(Methyl-d3)tetrahydrofolic acid
Catalogue No.	VQ-030862
CAS Number	1356019-97-0
IUPAC name	(2S)-2-[[4-[[2-amino-4-oxo-5-(trideuteriomethyl)-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
Molecular formula	C₂₀H₂₅N₇O₆
Molecular weight	462.5 g/mol
Exact mass	462.2055
Grade	Reference Standard
HSN code	38229090
InChIKey	ZNOVTXRBGFNYRX-WILDCZHSSA-N
SMILES	[2H]C([2H])([2H])N1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	136234042

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	7 / 10
TPSA	198 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-(Methyl-d3)tetrahydrofolic acid?

The CAS Registry Number of 5-(Methyl-d3)tetrahydrofolic acid is 1356019-97-0. It is also known as 5-(Methyl-d3)tetrahydrofolic Acid (Mixture of Diastereomers), 5-(Methyl-d3)Tetrahydrofolic Acid (Mixture of Diatereomers).

What is the molecular formula and molecular weight of 5-(Methyl-d3)tetrahydrofolic acid?

5-(Methyl-d3)tetrahydrofolic acid has the molecular formula C20H25N7O6 and a molecular weight of 462.5 g/mol. Its IUPAC name is (2S)-2-[[4-[[2-amino-4-oxo-5-(trideuteriomethyl)-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid.

What is 5-(Methyl-d3)tetrahydrofolic acid used for?

5-(Methyl-d3)tetrahydrofolic acid is supplied as a characterised reference material related to Folic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-(Methyl-d3)tetrahydrofolic acid can I order?

We supply 5-(Methyl-d3)tetrahydrofolic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-(Methyl-d3)tetrahydrofolic acid?

Yes. Every lot of 5-(Methyl-d3)tetrahydrofolic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-(Methyl-d3)tetrahydrofolic acid be shipped internationally?

Yes. We export 5-(Methyl-d3)tetrahydrofolic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.