Aspartame-d3

About Aspartame-d3

Aspartame-d3 is a stable isotope labelled analogue related to Aspartame carrying the CAS registry number 1356841-28-5. The compound has the formula C14H18N2O5, corresponding to a molecular weight of 297.32 g/mol. Its systematic (IUPAC) name is (3S)-3-amino-4-oxo-4-[[(2S)-1-oxo-3-phenyl-1-(trideuteriomethoxy)propan-2-yl]amino]butanoic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Aspartame

View every impurity, metabolite and intermediate we list for Aspartame.

Aspartame impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Aspartame-d3
Catalogue No.	VQ-043378
CAS Number	1356841-28-5
IUPAC name	(3S)-3-amino-4-oxo-4-[[(2S)-1-oxo-3-phenyl-1-(trideuteriomethoxy)propan-2-yl]amino]butanoic acid
Molecular formula	C₁₄H₁₈N₂O₅
Molecular weight	297.32 g/mol
Exact mass	297.1404
Grade	Reference Standard
HSN code	38229090
InChIKey	IAOZJIPTCAWIRG-JRDZZGLNSA-N
SMILES	[2H]C([2H])([2H])OC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(=O)O)N
PubChem CID	46780483

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.7
H-bond donors / acceptors	3 / 6
TPSA	119 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aspartame-d3?

The CAS Registry Number of Aspartame-d3 is 1356841-28-5. It is also known as (~2~H_3_)Methyl L-alpha-aspartyl-L-phenylalaninate.

What is the molecular formula and molecular weight of Aspartame-d3?

Aspartame-d3 has the molecular formula C14H18N2O5 and a molecular weight of 297.32 g/mol. Its IUPAC name is (3S)-3-amino-4-oxo-4-[[(2S)-1-oxo-3-phenyl-1-(trideuteriomethoxy)propan-2-yl]amino]butanoic acid.

What is Aspartame-d3 used for?

Aspartame-d3 is supplied as a characterised reference material related to Aspartame. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aspartame-d3 can I order?

We supply Aspartame-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aspartame-d3?

Yes. Every lot of Aspartame-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aspartame-d3 be shipped internationally?

Yes. We export Aspartame-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.