Palonosetron EP Impurity D

About Palonosetron EP Impurity D

Palonosetron EP Impurity D is a pharmacopeial impurity of Palonosetron carrying the CAS registry number 135729-56-5 with a typical assay of 96%. The compound has the formula C19H22N2O, corresponding to a molecular weight of 294.4 g/mol. Its systematic (IUPAC) name is 2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one. Alternative names: Palonosetron USP Related Compound E and Dehydro Palonosetron.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Palonosetron, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Palonosetron EP Impurity D in 10 mg, 25 mg and 50 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Palonosetron EP Impurity D
Catalogue No.	VQ-006562
CAS Number	135729-56-5
Other CAS	135729-55-4
IUPAC name	2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one
Molecular formula	C₁₉H₂₂N₂O
Molecular weight	294.4 g/mol
Exact mass	294.1732
Grade	Reference Standard
Purity / assay	96%
HSN code	38229090
InChIKey	DIDFYSQVOPVZQB-QGZVFWFLSA-N
SMILES	C1CC2=C3C(=CN(C(=O)C3=CC=C2)[C@@H]4CN5CCC4CC5)C1
PubChem CID	148210

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 2
TPSA	23.6 Å²
Synonyms	(S)-2-(quinuclidin-3-yl)-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one, 2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one, (S)-2-(1-Azabicyclo[2.2.2]oct-3-yl)-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one, 2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl] 2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one, Palonosetron USP Related Compound E, Dehydro Palonosetron, 2-((3S)-1-Azabicyclo(2.2.2)oct-3-yl) 2,4,5,6-tetrahydro-1H-benzo(de)isoquinolin-1-one, Palonosetron Impurity 7, Palonosetron Impurity 56, (S)-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,4,5,6-tetrahydro1H-benz[de]isoquinolin-1-one, 2-((1R,3S,4R)-quinuclidin-3-yl)-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one, 2-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Palonosetron EP Impurity D?

The CAS Registry Number of Palonosetron EP Impurity D is 135729-56-5. It is also known as (S)-2-(quinuclidin-3-yl)-2,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-1-one, 2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one, (S)-2-(1-Azabicyclo[2.2.2]oct-3-yl)-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one.

What is the molecular formula and molecular weight of Palonosetron EP Impurity D?

Palonosetron EP Impurity D has the molecular formula C19H22N2O and a molecular weight of 294.4 g/mol. Its IUPAC name is 2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one.

What is Palonosetron EP Impurity D used for?

Palonosetron EP Impurity D is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Palonosetron EP Impurity D can I order?

We supply Palonosetron EP Impurity D in Reference Standard (96%) grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Palonosetron EP Impurity D?

Yes. Every lot of Palonosetron EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Palonosetron EP Impurity D be shipped internationally?

Yes. We export Palonosetron EP Impurity D worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.