Sildenafil EP Impurity D

Name: Sildenafil EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-006692

About Sildenafil EP Impurity D

Sildenafil EP Impurity D (CAS 1357931-55-5) is a pharmacopeial impurity of Sildenafil offered by Vaqora Chemicals with a typical assay of 99.5%. Formula C17H20N4O5S, molecular weight 392.4 g/mol. Systematically, it is named 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonic acid. Common synonyms include Desmethylpiperazinyl Sildenafil Sulfonic Acid and Demethylpiperazinyl Sildenafil Sulfonic Acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Sildenafil impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Sildenafil EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Sildenafil

View every impurity, metabolite and intermediate we list for Sildenafil.

Sildenafil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sildenafil EP Impurity D
Catalogue No.	VQ-006692
CAS Number	1357931-55-5
IUPAC name	4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonic acid
Molecular formula	C₁₇H₂₀N₄O₅S
Molecular weight	392.4 g/mol
Exact mass	392.1154
Grade	Reference Standard
Purity / assay	99.5%
HSN code	38229090
InChIKey	DFABUTFBIDMPKZ-UHFFFAOYSA-N
SMILES	CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)O)OCC)C
PubChem CID	135565561

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	2 / 7
TPSA	131 Å²
Synonyms	Desmethylpiperazinyl Sildenafil Sulfonic Acid, Demethylpiperazinyl Sildenafil Sulfonic Acid, Des(methylpiperazinyl) sildenafil acid, Sildenafil desmethylpiperazinyl sulfonic acid, Sildenafil citrate impurity D, 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonic acid, 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonic acid, Demethylpiperaziny sildenafil sulfonic acid, Sildenafil-demethylpiperazinyl-sulfonic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sildenafil EP Impurity D?

The CAS Registry Number of Sildenafil EP Impurity D is 1357931-55-5. It is also known as Desmethylpiperazinyl Sildenafil Sulfonic Acid, Demethylpiperazinyl Sildenafil Sulfonic Acid, Des(methylpiperazinyl) sildenafil acid.

What is the molecular formula and molecular weight of Sildenafil EP Impurity D?

Sildenafil EP Impurity D has the molecular formula C17H20N4O5S and a molecular weight of 392.4 g/mol. Its IUPAC name is 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonic acid.

What is Sildenafil EP Impurity D used for?

Sildenafil EP Impurity D is supplied as a characterised reference material related to Sildenafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sildenafil EP Impurity D can I order?

We supply Sildenafil EP Impurity D in Reference Standard (99.5%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sildenafil EP Impurity D?

Yes. Every lot of Sildenafil EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sildenafil EP Impurity D be shipped internationally?

Yes. Sildenafil EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.