Pioglitazone EP Impurity B

Name: Pioglitazone EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-023501

About Pioglitazone EP Impurity B

Listed under CAS 136401-69-9, Pioglitazone EP Impurity B is a pharmacopeial impurity of Pioglitazone available from Vaqora Chemicals. The compound has the formula C19H18N2O3S, corresponding to a molecular weight of 354.4 g/mol. Its systematic (IUPAC) name is (5Z)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione. It is also known as Pioglitazone - Impurity B or Pioglitazone Impurity B (Z Isomer).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Pioglitazone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Pioglitazone EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Pioglitazone

View every impurity, metabolite and intermediate we list for Pioglitazone.

Pioglitazone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Pioglitazone EP Impurity B
Catalogue No.	VQ-023501
CAS Number	136401-69-9
IUPAC name	(5Z)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione
Molecular formula	C₁₉H₁₈N₂O₃S
Molecular weight	354.4 g/mol
Exact mass	354.1038
Grade	Reference Standard
HSN code	38229090
InChIKey	YNTUJOCADSTMCL-BOPFTXTBSA-N
SMILES	CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)/C=C\3/C(=O)NC(=O)S3
PubChem CID	10937126

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	1 / 5
TPSA	93.6 Å²
Synonyms	Pioglitazone - Impurity B, Pioglitazone Impurity B (Z Isomer), Didehydropioglitazone, (5Z)-, (Z)-5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione, (5Z)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione, (5Z)-5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione, (5Z)-5-((4-(2-(5-Ethylpyridin-2-yl)ethoxy)phenyl)methylene)thiazolidine-2,4-dione, 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methylene)-, (5Z)-, (5Z)-didehydropioglitazone, 5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pioglitazone EP Impurity B?

The CAS Registry Number of Pioglitazone EP Impurity B is 136401-69-9. It is also known as Pioglitazone - Impurity B, Pioglitazone Impurity B (Z Isomer), Didehydropioglitazone, (5Z)-.

What is the molecular formula and molecular weight of Pioglitazone EP Impurity B?

Pioglitazone EP Impurity B has the molecular formula C19H18N2O3S and a molecular weight of 354.4 g/mol. Its IUPAC name is (5Z)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione.

What is Pioglitazone EP Impurity B used for?

Pioglitazone EP Impurity B is supplied as a characterised reference material related to Pioglitazone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pioglitazone EP Impurity B can I order?

We supply Pioglitazone EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pioglitazone EP Impurity B?

Yes. Every lot of Pioglitazone EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pioglitazone EP Impurity B be shipped internationally?

Yes. Pioglitazone EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.