Escitalopram EP Impurity I

About Escitalopram EP Impurity I

Escitalopram EP Impurity I is a pharmacopeial impurity of Escitalopram carrying the CAS registry number 1370643-22-3. Formula C20H21FN2O, molecular weight 324.4 g/mol. Systematically, it is named 4-[(Z)-4-(dimethylamino)-1-(4-fluorophenyl)but-1-enyl]-3-(hydroxymethyl)benzonitrile. It is also known as Escitalopram Olefinic impurity or Escitalopram - Impurity I (Freebase).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Escitalopram to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Escitalopram EP Impurity I is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Escitalopram

View every impurity, metabolite and intermediate we list for Escitalopram.

Escitalopram impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Escitalopram EP Impurity I
Catalogue No.	VQ-021173
CAS Number	1370643-22-3
IUPAC name	4-[(Z)-4-(dimethylamino)-1-(4-fluorophenyl)but-1-enyl]-3-(hydroxymethyl)benzonitrile
Molecular formula	C₂₀H₂₁FN₂O
Molecular weight	324.4 g/mol
Exact mass	324.1638
Grade	Reference Standard
HSN code	38229090
InChIKey	IAICSOQOSARWDY-PVOVUMCXSA-N
SMILES	CN(C)CC/C=C(/C1=CC=C(C=C1)F)\C2=C(C=C(C=C2)C#N)CO
PubChem CID	11472790

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	1 / 4
TPSA	47.3 Å²
Synonyms	Escitalopram Olefinic impurity, Escitalopram - Impurity I (Freebase), 4-[(1Z)-4-(Dimethylamino)-1-(4-fluorophenyl)but-1-en-1-yl]-3-(hydroxymethyl)benzonitrile, (Z)-4-(4-(dimethylamino)-1-(4-fluorophenyl)but-1-en-1-yl)-3-(hydroxymethyl)benzonitrile, 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-buten-1-yl]-3-(hydroxymethyl)-benzonitrile, 4-[(1Z)-4-(Dimethylamino)-1-(4-fluorophenyl)-1-buten-1-yl]-3-(hydroxymethyl)benzonitrile, 4-[[Z]-4-[Dimethylamino]-1-[4-fluorophenyl]but-1-enyl]-3-[hydroxymethyl]benzonitrile

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Escitalopram EP Impurity I?

The CAS Registry Number of Escitalopram EP Impurity I is 1370643-22-3. It is also known as Escitalopram Olefinic impurity, Escitalopram - Impurity I (Freebase), 4-[(1Z)-4-(Dimethylamino)-1-(4-fluorophenyl)but-1-en-1-yl]-3-(hydroxymethyl)benzonitrile.

What is the molecular formula and molecular weight of Escitalopram EP Impurity I?

Escitalopram EP Impurity I has the molecular formula C20H21FN2O and a molecular weight of 324.4 g/mol. Its IUPAC name is 4-[(Z)-4-(dimethylamino)-1-(4-fluorophenyl)but-1-enyl]-3-(hydroxymethyl)benzonitrile.

What is Escitalopram EP Impurity I used for?

Escitalopram EP Impurity I is supplied as a characterised reference material related to Escitalopram. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Escitalopram EP Impurity I can I order?

We supply Escitalopram EP Impurity I in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Escitalopram EP Impurity I?

Yes. Every lot of Escitalopram EP Impurity I is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Escitalopram EP Impurity I be shipped internationally?

Yes. We export Escitalopram EP Impurity I worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.