2-Amidinopyrimidine hydrochloride

Name: 2-Amidinopyrimidine hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-032941

About 2-Amidinopyrimidine hydrochloride

2-Amidinopyrimidine hydrochloride (CAS 138588-40-6) is an impurity of Bosentan offered by Vaqora Chemicals. Its molecular formula is C5H7ClN4 and its molecular weight is 158.59 g/mol. It is also known as 2-Pyrimidinecarboximidamide Hydrochloride or pyrimidine-2-carboximidamide hydrochloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Bosentan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Amidinopyrimidine hydrochloride
Catalogue No.	VQ-032941
CAS Number	138588-40-6
IUPAC name	pyrimidine-2-carboximidamide;hydrochloride
Molecular formula	C₅H₇ClN₄
Molecular weight	158.59 g/mol
Exact mass	158.0359
Grade	Reference Standard
HSN code	38229090
InChIKey	LZIYBABLVXXFGZ-UHFFFAOYSA-N
SMILES	C1=CN=C(N=C1)C(=N)N.Cl
PubChem CID	21983731

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 3
TPSA	75.7 Å²
Synonyms	2-Pyrimidinecarboximidamide Hydrochloride, 2-Pyrimidinecarboximidamide, hydrochloride (1:1), pyrimidine-2-carboximidamide hydrochloride, 2-Pyrimidinecarboximidamide, monohydrochloride, pyrimidine-2-carboxamidine hydrochloride, 2-Amidinopyrimidine, HCl, 2-Pyrimidinecarboximidamide HCl, CS-M122, CS-M1221, pyrimidin-2-carboxamidine hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Amidinopyrimidine hydrochloride?

The CAS Registry Number of 2-Amidinopyrimidine hydrochloride is 138588-40-6. It is also known as 2-Pyrimidinecarboximidamide Hydrochloride, 2-Pyrimidinecarboximidamide, hydrochloride (1:1), pyrimidine-2-carboximidamide hydrochloride.

What is the molecular formula and molecular weight of 2-Amidinopyrimidine hydrochloride?

2-Amidinopyrimidine hydrochloride has the molecular formula C5H7ClN4 and a molecular weight of 158.59 g/mol.

What is 2-Amidinopyrimidine hydrochloride used for?

2-Amidinopyrimidine hydrochloride is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Amidinopyrimidine hydrochloride can I order?

We supply 2-Amidinopyrimidine hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Amidinopyrimidine hydrochloride?

Yes. Every lot of 2-Amidinopyrimidine hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Amidinopyrimidine hydrochloride be shipped internationally?

Yes. 2-Amidinopyrimidine hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.