Tenofovir Alafenamide Fumarate

Name: Tenofovir Alafenamide Fumarate
Brand: Vaqora Chemicals
SKU: VQ-030466

About Tenofovir Alafenamide Fumarate

Listed under CAS 1392275-56-7, Tenofovir Alafenamide Fumarate is an impurity of Tenofovir available from Vaqora Chemicals. With the molecular formula C46H62N12O14P2, it has a molar mass of 1069.0 g/mol. It is also known as Tenofovir Alafenamide Hemifumarate or GS-7340 Hemifumarate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Tenofovir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tenofovir Alafenamide Fumarate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tenofovir

View every impurity, metabolite and intermediate we list for Tenofovir.

Tenofovir impurities

Specifications & identifiers

Chemical identifiers
Product name	Tenofovir Alafenamide Fumarate
Catalogue No.	VQ-030466
CAS Number	1392275-56-7
IUPAC name	(E)-but-2-enedioic acid;bis(propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate)
Molecular formula	C₄₆H₆₂N₁₂O₁₄P₂
Molecular weight	1069 g/mol
Exact mass	1068.3984
Grade	Reference Standard
HSN code	38229090
InChIKey	SVUJNSGGPUCLQZ-FQQAACOVSA-N
SMILES	C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C(=C/C(=O)O)\C(=O)O
PubChem CID	71492247

Physical properties
Physical form	Solid
H-bond donors / acceptors	6 / 24
TPSA	362 Å²
Synonyms	Tenofovir Alafenamide Hemifumarate, Emtricitabine-Tenofovir Alafenamide Hemifumarate, GS-7340 Hemifumarate, EX-A2641, TAF(Tenofovir Alafenamide Hemifumarate), Tenofovir alafenamide fumarate (JAN/USAN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264, P270, P301 + P317, P319, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tenofovir Alafenamide Fumarate?

The CAS Registry Number of Tenofovir Alafenamide Fumarate is 1392275-56-7. It is also known as Tenofovir Alafenamide Hemifumarate, Emtricitabine-Tenofovir Alafenamide Hemifumarate, GS-7340 Hemifumarate.

What is the molecular formula and molecular weight of Tenofovir Alafenamide Fumarate?

Tenofovir Alafenamide Fumarate has the molecular formula C46H62N12O14P2 and a molecular weight of 1069 g/mol.

What is Tenofovir Alafenamide Fumarate used for?

Tenofovir Alafenamide Fumarate is supplied as a characterised reference material related to Tenofovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tenofovir Alafenamide Fumarate can I order?

We supply Tenofovir Alafenamide Fumarate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tenofovir Alafenamide Fumarate?

Yes. Every lot of Tenofovir Alafenamide Fumarate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tenofovir Alafenamide Fumarate be shipped internationally?

Yes. Tenofovir Alafenamide Fumarate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.