Candesartan Cilexetil EP Impurity I

Name: Candesartan Cilexetil EP Impurity I
Brand: Vaqora Chemicals
SKU: VQ-006281

About Candesartan Cilexetil EP Impurity I

Vaqora Chemicals supplies Candesartan Cilexetil EP Impurity I, a pharmacopeial impurity of Candesartan registered under CAS number 139481-69-9 with a typical assay of 96.2%. Formula C25H22N6O3, molecular weight 454.5 g/mol. The IUPAC name is methyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate. It is also known as Candesartan Methyl Ester or Methyl candesartan.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Candesartan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Candesartan

View every impurity, metabolite and intermediate we list for Candesartan.

Candesartan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Candesartan Cilexetil EP Impurity I
Catalogue No.	VQ-006281
CAS Number	139481-69-9
IUPAC name	methyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
Molecular formula	C₂₅H₂₂N₆O₃
Molecular weight	454.5 g/mol
Exact mass	454.1753
Grade	Reference Standard
Purity / assay	96.2%
HSN code	38229090
InChIKey	RBPFEPGTRLLUKI-UHFFFAOYSA-N
SMILES	CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC
PubChem CID	15654696

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	1 / 7
TPSA	108 Å²
Synonyms	Methyl 1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-2-ethoxybenzimidazole-7-carboxylate, Methyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate, Candesartan Methyl Ester, Methyl candesartan, Candesartan cilexetil impurity I, Methyl 1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-ethoxybenzimidazole-7-carboxylate, Methyl 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)benzimidazole-7-carboxylate, Ethyl-2-ethoxy-1-[[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]benzimidazole]-7-carboxylate, ethyl2-ethoxy-1-[[2'-(1h-tetrazol-5-yl)methyl]benzimidazole-7-carboxylate, Methyl 2-ethoxy-1-[[2'-(1 H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate, methyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl]benzimidazole-7-carboxylate, methyl 2-ethoxy-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methylbenzimidazole-7carboxylate

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Candesartan Cilexetil EP Impurity I?

The CAS Registry Number of Candesartan Cilexetil EP Impurity I is 139481-69-9. It is also known as Methyl 1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-2-ethoxybenzimidazole-7-carboxylate, Methyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate, Candesartan Methyl Ester.

What is the molecular formula and molecular weight of Candesartan Cilexetil EP Impurity I?

Candesartan Cilexetil EP Impurity I has the molecular formula C25H22N6O3 and a molecular weight of 454.5 g/mol. Its IUPAC name is methyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate.

What is Candesartan Cilexetil EP Impurity I used for?

Candesartan Cilexetil EP Impurity I is supplied as a characterised reference material related to Candesartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Candesartan Cilexetil EP Impurity I can I order?

We supply Candesartan Cilexetil EP Impurity I in Reference Standard (96.2%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Candesartan Cilexetil EP Impurity I?

Yes. Every lot of Candesartan Cilexetil EP Impurity I is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Candesartan Cilexetil EP Impurity I be shipped internationally?

Yes. Candesartan Cilexetil EP Impurity I is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.