5'-Epi Lamivudine

About 5'-Epi Lamivudine

5'-Epi Lamivudine is an impurity of Lamivudine carrying the CAS registry number 139757-68-9. The compound has the formula C8H11N3O3S, corresponding to a molecular weight of 229.26 g/mol. Systematically, it is named 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one. It is also known as Lamivudine 5-Epimer or alpha-L-Oxathionyl-cytidine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Lamivudine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lamivudine

View every impurity, metabolite and intermediate we list for Lamivudine.

Lamivudine impurities

Specifications & identifiers

Chemical identifiers
Product name	5'-Epi Lamivudine
Catalogue No.	VQ-026340
CAS Number	139757-68-9
IUPAC name	4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Molecular formula	C₈H₁₁N₃O₃S
Molecular weight	229.26 g/mol
Exact mass	229.0521
Grade	Reference Standard
HSN code	38229090
InChIKey	JTEGQNOMFQHVDC-RNFRBKRXSA-N
SMILES	C1[C@@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N
PubChem CID	441224

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	2 / 4
TPSA	113 Å²
Synonyms	Lamivudine 5-Epimer, trans-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane, alpha-L-Oxathionyl-cytidine, 2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-trans)-, alpha-L-(+)-(2R,5R)-1-(2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine, 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-trans)-, 4'-Epi Lamivudine, 4-Amino-1-((2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one, 4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, .alpha.-L-Oxathionyl-cytidine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5'-Epi Lamivudine?

The CAS Registry Number of 5'-Epi Lamivudine is 139757-68-9. It is also known as Lamivudine 5-Epimer, trans-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane, alpha-L-Oxathionyl-cytidine.

What is the molecular formula and molecular weight of 5'-Epi Lamivudine?

5'-Epi Lamivudine has the molecular formula C8H11N3O3S and a molecular weight of 229.26 g/mol. Its IUPAC name is 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.

What is 5'-Epi Lamivudine used for?

5'-Epi Lamivudine is supplied as a characterised reference material related to Lamivudine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5'-Epi Lamivudine can I order?

We supply 5'-Epi Lamivudine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5'-Epi Lamivudine?

Yes. Every lot of 5'-Epi Lamivudine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5'-Epi Lamivudine be shipped internationally?

Yes. We export 5'-Epi Lamivudine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.