Acalabrutinib Pyrrolidine Impurity

Name: Acalabrutinib Pyrrolidine Impurity
Brand: Vaqora Chemicals
SKU: VQ-004339

About Acalabrutinib Pyrrolidine Impurity

Acalabrutinib Pyrrolidine Impurity is an impurity of Acalabrutinib carrying the CAS registry number 1420478-90-5. Formula C22H21N7O, molecular weight 399.4 g/mol. Its systematic (IUPAC) name is 4-[8-amino-3-[(2S)-pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide. Alternative names: Axitinib Impurity N1 and pyridin-2-yl-benzamide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Acalabrutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Acalabrutinib Pyrrolidine Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Acalabrutinib Pyrrolidine Impurity
Catalogue No.	VQ-004339
CAS Number	1420478-90-5
IUPAC name	4-[8-amino-3-[(2S)-pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
Molecular formula	C₂₂H₂₁N₇O
Molecular weight	399.4 g/mol
Exact mass	399.1808
Grade	Reference Standard
HSN code	38229090
InChIKey	RWBYECCAYSUTDK-INIZCTEOSA-N
SMILES	C1C[C@H](NC1)C2=NC(=C3N2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=CC=CC=N5
PubChem CID	71226368

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	3 / 6
TPSA	110 Å²
Synonyms	4-[8-Amino-3-(2S)-2-pyrrolidinylimidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide, (S)-4-(8-amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide, Benzamide, 4-[8-amino-3-(2S)-2-pyrrolidinylimidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-, (S)-4-(8-Amino-3-pyrrolidin-2-yl-imidazo[1,5-a]pyrazin-1-yl)-N-pyridin-2-yl-benzamide, Axitinib Impurity N1, pyridin-2-yl-benzamide, acarabrutinib intermediate, Acalabrutinib intermediate, (S)-4-(8-Amino-3-pyrrolidin-2-yl-imidazo[1,5-a]pyrazin-1-yl)-N-, (S)-4-(8-Amino-3-pyrrolidin-2-yl-imidazo[1,5-a]pyrazin-1-yl)..., (S)-4-[8-Amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl]-N-(2-pyridyl)benzamide, 4-[8-amino-3-(2S)-2-pyrrolidinylimidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-Benzamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acalabrutinib Pyrrolidine Impurity?

The CAS Registry Number of Acalabrutinib Pyrrolidine Impurity is 1420478-90-5. It is also known as 4-[8-Amino-3-(2S)-2-pyrrolidinylimidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide, (S)-4-(8-amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide, Benzamide, 4-[8-amino-3-(2S)-2-pyrrolidinylimidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-.

What is the molecular formula and molecular weight of Acalabrutinib Pyrrolidine Impurity?

Acalabrutinib Pyrrolidine Impurity has the molecular formula C22H21N7O and a molecular weight of 399.4 g/mol. Its IUPAC name is 4-[8-amino-3-[(2S)-pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide.

What is Acalabrutinib Pyrrolidine Impurity used for?

Acalabrutinib Pyrrolidine Impurity is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acalabrutinib Pyrrolidine Impurity can I order?

We supply Acalabrutinib Pyrrolidine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acalabrutinib Pyrrolidine Impurity?

Yes. Every lot of Acalabrutinib Pyrrolidine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acalabrutinib Pyrrolidine Impurity be shipped internationally?

Yes. We export Acalabrutinib Pyrrolidine Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.