Osimertinib Metabolite M3
Synonyms: Osimertinib Desmethyl Impurity · Osimertinib N Desmethyl Impurity · Osimertinib Impurity 4 · EX-A6199
Osimertinib Metabolite M3 (CAS 1421373-99-0) – Osimertinib impurity standard. C27H31N7O2, MW 485.6. COA included. Worldwide shipping from Vaqora Chemicals.
About Osimertinib Metabolite M3
Osimertinib Metabolite M3 (CAS 1421373-99-0) is a metabolite or degradation product of Osimertinib offered by Vaqora Chemicals. Formula C27H31N7O2, molecular weight 485.6 g/mol. It is also known as Osimertinib Desmethyl Impurity or Osimertinib N Desmethyl Impurity.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.
Analytical teams use this compound to identify metabolites and degradants of Osimertinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Osimertinib Metabolite M3 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Industries
View every impurity, metabolite and intermediate we list for Osimertinib.
Osimertinib impuritiesSpecifications & identifiers
| Product name | Osimertinib Metabolite M3 |
|---|---|
| Catalogue No. | VQ-032309 |
| CAS Number | 1421373-99-0 |
| IUPAC name | N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide |
| Molecular formula | C27H31N7O2 |
| Molecular weight | 485.6 g/mol |
| Exact mass | 485.2539 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | ZROCWKZRGJYPTG-UHFFFAOYSA-N |
| SMILES | CNCCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C)OC |
| PubChem CID | 71496459 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 3.3 |
| H-bond donors / acceptors | 3 / 7 |
| TPSA | 96.3 Ų |
Documents
Frequently asked questions
What is the CAS number of Osimertinib Metabolite M3?
The CAS Registry Number of Osimertinib Metabolite M3 is 1421373-99-0. It is also known as Osimertinib Desmethyl Impurity, Osimertinib N Desmethyl Impurity, Osimertinib Impurity 4.
What is the molecular formula and molecular weight of Osimertinib Metabolite M3?
Osimertinib Metabolite M3 has the molecular formula C27H31N7O2 and a molecular weight of 485.6 g/mol. Its IUPAC name is N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide.
What is Osimertinib Metabolite M3 used for?
Osimertinib Metabolite M3 is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Osimertinib Metabolite M3 can I order?
We supply Osimertinib Metabolite M3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Osimertinib Metabolite M3?
Yes. Every lot of Osimertinib Metabolite M3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Osimertinib Metabolite M3 be shipped internationally?
Yes. We export Osimertinib Metabolite M3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about Osimertinib Metabolite M3
We reply within one business day with price, pack options, lead time and documentation.
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