5'-Hydroxyphenyl Carvedilol

About 5'-Hydroxyphenyl Carvedilol

5'-Hydroxyphenyl Carvedilol is a metabolite or degradation product of Carvedilol carrying the CAS registry number 142227-51-8. With the molecular formula C24H26N2O5, it has a molar mass of 422.5 g/mol. Its systematic (IUPAC) name is 3-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxyphenol. Alternative names: 5'-Hydroxycarvedilol and 5'-Hydroxyphenylcarvedilol (M5).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Carvedilol, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Carvedilol

View every impurity, metabolite and intermediate we list for Carvedilol.

Carvedilol impurities

Specifications & identifiers

Chemical identifiers
Product name	5'-Hydroxyphenyl Carvedilol
Catalogue No.	VQ-021079
CAS Number	142227-51-8
IUPAC name	3-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxyphenol
Molecular formula	C₂₄H₂₆N₂O₅
Molecular weight	422.5 g/mol
Exact mass	422.1842
Grade	Reference Standard
HSN code	38229090
InChIKey	PVUVZUBTCLBJMT-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1)O)OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O
PubChem CID	4181439

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	4 / 6
TPSA	96 Å²
Synonyms	5'-Hydroxycarvedilol, Phenol, 3-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxy-, 3-(2-((3-((9H-Carbazol-4-yl)oxy)-2-hydroxypropyl)amino)ethoxy)-4-methoxyphenol, 3-[2-({3-[(9H-Carbazol-4-yl)oxy]-2-hydroxypropyl}amino)ethoxy]-4-methoxyphenol, 5'-Hydroxyphenylcarvedilol (M5), 3-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxy-propyl]amino]ethoxy]-4-methoxy-phenol

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P273, P319, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5'-Hydroxyphenyl Carvedilol?

The CAS Registry Number of 5'-Hydroxyphenyl Carvedilol is 142227-51-8. It is also known as 5'-Hydroxycarvedilol, Phenol, 3-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxy-, 3-(2-((3-((9H-Carbazol-4-yl)oxy)-2-hydroxypropyl)amino)ethoxy)-4-methoxyphenol.

What is the molecular formula and molecular weight of 5'-Hydroxyphenyl Carvedilol?

5'-Hydroxyphenyl Carvedilol has the molecular formula C24H26N2O5 and a molecular weight of 422.5 g/mol. Its IUPAC name is 3-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxyphenol.

What is 5'-Hydroxyphenyl Carvedilol used for?

5'-Hydroxyphenyl Carvedilol is supplied as a characterised reference material related to Carvedilol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5'-Hydroxyphenyl Carvedilol can I order?

We supply 5'-Hydroxyphenyl Carvedilol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5'-Hydroxyphenyl Carvedilol?

Yes. Every lot of 5'-Hydroxyphenyl Carvedilol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5'-Hydroxyphenyl Carvedilol be shipped internationally?

Yes. 5'-Hydroxyphenyl Carvedilol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.